Journal
TRENDS IN BIOTECHNOLOGY
Volume 37, Issue 5, Pages 518-531Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2018.10.010
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Funding
- Purdue University Agricultural Research Programs [10646, 10677]
- CAPES, Brazil [12981/13-3]
- DOE [DE-EE0008256]
- Department of Agricultural and Biological Engineering
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Lignin is central to overcoming recalcitrance in the enzyme hydrolysis of lignocellulose. While the term implies a physical barrier in the cell wall structure, there are also important biochemical components that direct interactions between lignin and the hydrolytic enzymes that attack cellulose in plant cell walls. Progress toward a deeper understanding of the lignin synthesis pathway - and the consistency between a range of observations over the past 40 years in the very extensive literature on cellulose hydrolysis - is resulting in advances in reducing a major impediment to cellulose conversion: the cost of enzymes. This review addresses lignin and its role in the hydrolysis of hardwood and other lignocellulosic residues.
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