Strategies in liquid chromatographic methods for the analysis of biogenic amines without and with derivatization

Covering the literature from 2011 until recently, this review highlights the analytical strategies that have been adopted for the extraction and analysis by high performance liquid chromatography comprising without or with derivatization of biogenic amines in real samples of food and beverages. The alternative ways of detection by tandem mass spectrometry, potential of multiple reaction monitoring and extracted ion chromatograms have been utilized when analyses performed without any derivatization. The reagents employed for derivatization differ widely in their structures, involve a variety of reaction mechanism, and allow detection by UV-absorption, fluorescence or mass spectrometry. The development of such a large number of reagents for a single class of analytes demonstrates the continued endeavours to overcome the implicit difficulties associated with low molar mass and polar analytes in complex sample matrices, and the inherent importance of the analysis of biogenic amines. The discussion presented will allow the alternative techniques to be adopted for particular biogenic amines samples, and have better control over selectivity and sensitivity of the method. (c) 2018 Elsevier B.V. All rights reserved.