4.4 Article

Viscosity measurements using a two-photon ratiometric fluorescent sensor with two rotors

Journal

TETRAHEDRON LETTERS
Volume 59, Issue 52, Pages 4540-4544

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2018.11.009

Keywords

Fluorescence sensor; Viscosity; Ratiometric; Two photon

Funding

  1. Special Fund for Agroscientific Research in the Public Interest [201503108]
  2. National Natural Science Foundation of China [51678163, U1701243]
  3. Guangdong Provincial Science and Technology Project [2014A030308019, 2016B070701017, 2015A020215016]
  4. Special Foundation for the Science and Technology Innovation Leaders of Guangdong Province [2014TX01Z038]
  5. GDAS' Special Project of Science and Technology Development [2017GDASCX-0824, 2017GDASCX-0401]

Ask authors/readers for more resources

A new ratiometric two-photon fluorescence sensor, Qca-Cy2, comprised of a hybrid cyanine-carbazole platform with two rotating sites is described. Qca-Cy2 can report on mitochondrial viscosity within live cells, as well as in living tissues at depths of 50-130 mu m by ratiometric fluorescence imaging using two-photon microscopy. (C) 2018 Elsevier Ltd. All rights reserved.

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