Journal
TETRAHEDRON
Volume 75, Issue 9, Pages 1115-1121Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2019.01.008
Keywords
Flavin-dependent enzymes; Biocatalysis; Monooxygenases; Halogenases; Ene-reductase; Monoamine oxidases; Baeyer-Villiger monooxygenases
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Funding
- University of Michigan Life Sciences Institute
- National Institutes of Health [R35 GM124880]
- National Institutes of Health Chemistry Biology Interface Training Grant [T32 GM008597]
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The diverse chemistry possible with flavin cofactors positions flavin-dependent enzymes as versatile synthetic tools. This focused review highlights applications of flavin-dependent enzymes in organic synthesis. Select examples of monoamine oxidases, ene-reductases, monooxygenases and halogenases in target-oriented synthesis are presented. (C) 2019 Published by Elsevier Ltd.
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