Journal
SKIN RESEARCH AND TECHNOLOGY
Volume 25, Issue 2, Pages 111-117Publisher
WILEY
DOI: 10.1111/srt.12626
Keywords
antimicrobial peptide; skin barrier; skin disease; skin immune defense; wound healing
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This review presents the current state of knowledge regarding multifunctional role of human skin antimicrobial peptides (AMPs), including (a) protection from microbial infection, (b) improvement of skin barrier homoeostasis, (c) modulation of inflammation responses, and (d) promotion of wound healing. In addition, association of AMPs with skin diseases as well as challenges and future prospects for AMP therapeutics has also been discussed.
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