High throughput and label-free particle sensor based on microwave resonators

We developed a novel particle sensor based on micro channels embedded in microwave resonators, which are fabricated by standard print circuit board manufacturing technology. The sensing frequency falls in the range 2-4 GHz, the widely used microwave S band. A 70 mu m-particle can produce a frequency shift of 0.5 MHz in a sensor with 150 mu m channel size, with a dwell time of 0.5 ms by using double split ring resonators. These resonator sensors may employ phase-locked loop in achieving a higher detection resolution. (C) 2018 Elsevier B.V. All rights reserved.