4.3 Review

Miscarriage chromosome testing: Indications, benefits and methodologies

Journal

SEMINARS IN PERINATOLOGY
Volume 43, Issue 2, Pages 101-104

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.semperi.2018.12.007

Keywords

Miscarriage; Recurrent Pregnancy Loss; Aneuploidy; Genetics

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Rapid advances in genomics have expanded the use of chromosome testing following miscarriage. In addition to conventional cytogenetics, the availability of single nucleotide polymorphism microarray technology and array comparative geneomic hybridization have provided further options for clinicians. This review will cover the indications for testing and the advantages/disadvantages of the various methodologies available. (C) 2018 Elsevier Inc. All rights reserved.

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