4.2 Review

Diagnostic histochemistry: A historical perspective

Journal

SEMINARS IN DIAGNOSTIC PATHOLOGY
Volume 35, Issue 6, Pages 354-359

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.semdp.2018.10.007

Keywords

Histochemistry; Cytochemistry; Histology; Biochemistry

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Histochemistry has a history which, in some ways, goes back to ancient times. The desire for humans to understand the workings of their bodies, and the roles that various chemicals have in them, is long-standing. This review considers the evolution of histochemistry and cytochemistry as scientific disciplines, culminating in the pairing of those techniques with basic biochemistry. They have served as the bases for a synthesis of microscopy, chemistry, immunology, and molecular biology, particularly in the practice of anatomic pathology.

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