Journal
SCIENCE
Volume 363, Issue 6423, Pages 140-140Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aar3932
Keywords
-
Categories
Funding
- HHMI
- Else Kroner Fresenius Foundation
- Blavatnik Family Foundation
- NIH [T32 AI007019, K08 AI128745]
- Gruber Science Fellowship
Ask authors/readers for more resources
Metabolism is at the core of all biological functions. Anabolic metabolism uses building blocks that are either derived from nutrients or synthesized de novo to produce the biological infrastructure, whereas catabolic metabolism generates energy to fuel all biological processes. Distinct metabolic programs are required to support different biological functions. Thus, recent studies have revealed how signals regulating cell quiescence, proliferation, and differentiation also induce the appropriate metabolic programs. In particular, a wealth of new studies in the field of immunometabolism has unveiled many examples of the connection among metabolism, cell fate decisions, and organismal physiology. We discuss these findings under a unifying framework derived from the evolutionary and ecological principles of life history theory.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available