Related references
Note: Only part of the references are listed.Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling
George Dalton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Inflammaging and 'Garb-aging'
Claudio Franceschi et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)
Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
Ling Chen et al.
SCIENTIFIC REPORTS (2017)
Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease
Matthew J. Simon et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice
Sumihiro Maeda et al.
EMBO REPORTS (2016)
The in vivo effects of a fraction from Dioscorea spongiosa on glucocorticoid-induced osteoporosis
Na Han et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
The Choroid Plexus in Healthy and Diseased Brain
Charanjit Kaur et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2016)
Origin, fate and dynamics of macrophages at central nervous system interfaces
Tobias Goldmann et al.
NATURE IMMUNOLOGY (2016)
New tools for studying microglia in the mouse and human CNS
Mariko L. Bennett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Type I/II Interferon Balance in the Regulation of Brain Physiology and Pathology
Aleksandra Deczkowska et al.
TRENDS IN IMMUNOLOGY (2016)
The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease
Sandro Da Mesquita et al.
BRAIN BEHAVIOR AND IMMUNITY (2015)
Molecular Basis of Klotho: From Gene to Function in Aging
Yuechi Xu et al.
ENDOCRINE REVIEWS (2015)
Spatially Heterogeneous Choroid Plexus Transcriptomes Encode Positional Identity and Contribute to Regional CSF Production
Melody P. Lun et al.
JOURNAL OF NEUROSCIENCE (2015)
Neuroinflammation in Alzheimer's disease
Michael T. Heneka et al.
LANCET NEUROLOGY (2015)
Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity
Susan L. Patterson
NEUROPHARMACOLOGY (2015)
Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression
Anna Masso et al.
PLOS ONE (2015)
Neurocognitive Aging and the Hippocampus across Species
Stephanie L. Leal et al.
TRENDS IN NEUROSCIENCES (2015)
NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases
Amna Abderrazak et al.
REDOX BIOLOGY (2015)
Klotho Gene Deficiency Causes Salt-Sensitive Hypertension via Monocyte Chemotactic Protein-1/CC Chemokine Receptor 2-Mediated Inflammation
Xiaoli Zhou et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)
BioAge: Toward a multi-determined, mechanistic account of cognitive aging
Correne A. DeCarlo et al.
AGEING RESEARCH REVIEWS (2014)
Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho
Ci-Di Chen et al.
BIOCHEMISTRY (2014)
Interferons in the Central Nervous System: A Few Instruments Play Many Tunes
Trevor Owens et al.
GLIA (2014)
Expression of Nampt in Hippocampal and Cortical Excitatory Neurons Is Critical for Cognitive Function
Liana Roberts Stein et al.
JOURNAL OF NEUROSCIENCE (2014)
The Kidney Is the Principal Organ Mediating Klotho Effects
Karolina Lindberg et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)
Microglial priming in neurodegenerative disease
V. Hugh Perry et al.
NATURE REVIEWS NEUROLOGY (2014)
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
Marco Prinz et al.
NATURE REVIEWS NEUROSCIENCE (2014)
Klotho in the cerebrospinal fluid of adults with and without Alzheimer's disease
Richard D. Semba et al.
NEUROSCIENCE LETTERS (2014)
Aging-induced type I interferon response at the choroid plexus negatively affects brain function
Kuti Baruch et al.
SCIENCE (2014)
Thioredoxin/Txnip: redoxisome, as a redox switch for the pathogenesis of diseases
Eiji Yoshihara et al.
FRONTIERS IN IMMUNOLOGY (2014)
A new look at cerebrospinal fluid circulation
Thomas Brinker et al.
FLUIDS AND BARRIERS OF THE CNS (2014)
IFN-γ-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair
Gilad Kunis et al.
BRAIN (2013)
CNS-specific T cells shape brain function via the choroid plexus
Kuti Baruch et al.
BRAIN BEHAVIOR AND IMMUNITY (2013)
Expression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood
Sarah M. Clinton et al.
BRAIN RESEARCH (2013)
Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging
Yun-Hee Youm et al.
CELL METABOLISM (2013)
Impact of aging brain circuits on cognition
Rachel D. Samson et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2013)
The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice
Tso-Hsiao Chen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
Microglial Activation Milieu Controls Regulatory T Cell Responses
Friederike Ebner et al.
JOURNAL OF IMMUNOLOGY (2013)
A Dramatic Increase of C1q Protein in the CNS during Normal Aging
Alexander H. Stephan et al.
JOURNAL OF NEUROSCIENCE (2013)
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka et al.
NATURE (2013)
CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging
Kuti Baruch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells
Julien Pothlichet et al.
PLOS PATHOGENS (2013)
Bone Marrow-derived Macrophage Production
Virginie Trouplin et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)
Thioredoxin Interacting Protein: Redox Dependent and Independent Regulatory Mechanisms
Oded N. Spindel et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome
Christine M. Oslowski et al.
CELL METABOLISM (2012)
The immunology of neurodegeneration
Eva Czirr et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
David H. Cribbs et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Targeted Deletion of Klotho in Kidney Distal Tubule Disrupts Mineral Metabolism
Hannes Olauson et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)
Nuclear localization of Klotho in brain: an anti-aging protein
Dwight C. German et al.
NEUROBIOLOGY OF AGING (2012)
Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits
Julie A. Harris et al.
PLOS ONE (2012)
A molecular characterization of the choroid plexus and stress-induced gene regulation
M. Sathyanesan et al.
TRANSLATIONAL PSYCHIATRY (2012)
IRF7: activation, regulation, modification and function
S. Ning et al.
GENES AND IMMUNITY (2011)
Ablation of Cellular Prion Protein Does Not Ameliorate Abnormal Neural Network Activity or Cognitive Dysfunction in the J20 Line of Human Amyloid Precursor Protein Transgenic Mice
Moustapha Cisse et al.
JOURNAL OF NEUROSCIENCE (2011)
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki et al.
NATURE (2011)
Klotho suppresses RIG-I-mediated senescence-associated inflammation
Feng Liu et al.
NATURE CELL BIOLOGY (2011)
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Rongbin Zhou et al.
NATURE IMMUNOLOGY (2010)
The Inflammasomes: Guardians of the Body
Fablo Martinon et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines
Christopher J. Henry et al.
BRAIN BEHAVIOR AND IMMUNITY (2009)
Thioredoxin Interacting Protein (TXNIP) Induces Inflammation Through Chromatin Modification in Retinal Capillary Endothelial Cells Under Diabetic Conditions
Lorena Perrone et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Klotho suppresses TNF-α-induced expression of adhesion molecules in the endothelium and attenuates NF-κB activation
Yoshihiro Maekawa et al.
ENDOCRINE (2009)
Extra Renal Synthesis of 1,25-dihydroxyvitamin D and its Health Implications
Daniel D. Bikle
CLINICAL REVIEWS IN BONE AND MINERAL METABOLISM (2009)
Gene profile analysis implicates klotho as an important contributor to aging changes in brain white matter of the rhesus monkey
James A. Duce et al.
GLIA (2008)
Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice
M. Shiozaki et al.
NEUROSCIENCE (2008)
IL-1β is an essential mediator of the antineurogenic and anhedonic effects of stress
Ja Wook Koo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Klotho converts canonical FGF receptor into a specific receptor for FGF23
Itaru Urakawa et al.
NATURE (2006)
Regulation of fibroblast growth factor-23 signaling by Klotho
H Kurosu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cryopyrin activates the inflammasome in response to toxins and ATP
S Mariathasan et al.
NATURE (2006)
The choroid plexus in the rise, fall and repair of the brain
DF Emerich et al.
BIOESSAYS (2005)
Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane
A Imura et al.
FEBS LETTERS (2004)
Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice
SA Li et al.
CELL STRUCTURE AND FUNCTION (2004)
Cognition impairment in the genetic model of aging klotho gene mutant mice:: a role of oxidative stress
T Nagai et al.
FASEB JOURNAL (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)