4.8 Article

Mn(III)-Mediated Cascade Cyclization of 3-Isocyano-[1,1′-biphenyl]-2-carbonitrile with Arylboronic Acid: Construction of Pyrrolopyridine Derivatives

Journal

ORGANIC LETTERS
Volume 21, Issue 3, Pages 683-686

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b03868

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Funding

  1. National Natural Science Foundation of China [21772137, 21542015, 21672157]
  2. PAPD
  3. Project of Scientific and Technologic Infrastructure of Suzhou [SZS201708]
  4. Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions [16KJA1S0002]
  5. Soochow University
  6. State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials

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A Mn(III) mediated cascade cyclization of new designed multifunctionalized 3-isocyano-[1,1'-biphenyl]-2-carbonitrile with arylboronic acid to construct pyrrolopyridine derivatives is developed. A series of pyrroloporidine compounds have been constructed through the formation of two new C-C bonds and one C-N bond via a radical pathway.

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