Journal
ORGANIC LETTERS
Volume 20, Issue 22, Pages 6994-6997Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b02816
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21472137, 21532008, 21772142]
- National Basic Research Program of China [2014CB745100]
Ask authors/readers for more resources
A zinc-mediated Mannich-type transformation of 2,2,2-trifluorodiazoethane with a series of imines has been described. This method provides facile access to a wide range of trifluorodiazoethyl-substituted amines in moderate to high yields under mild conditions. The synthetic utility of the afforded adducts is demonstrated by further transformations to valuable beta-CF3-amines.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available