Journal
ORGANIC LETTERS
Volume 21, Issue 2, Pages 579-583Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b03985
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Funding
- Chinese National Natural Science Foundation [21202135, 21642010, 41576081]
- Fundamental Research Funds for the Central Universities [20720180083, 20720160034]
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The first facile and efficient Cu-catalyzed direct coupling of unprotected propargylic diols with H-phosphine oxides was developed, providing a practical approach to access structurally diverse 2,3-bis(diarylphosphynyl)-1,3-butadienes along with the formation of two new P-C-sp2 and two new C=C bonds under ligand- and base-free conditions.
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