Journal
OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA
Volume 45, Issue 4, Pages 613-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ogc.2018.07.004
Keywords
Reproductive aging; Perimenopause; Gonadotropins; Folliculogenesis
Categories
Funding
- National Institutes of Health (NIH), DHHS, through the National Institute on Aging (NIA)
- National Institute of Nursing Research (NINR)
- NIH Office of Research on Women's Health (ORWH) [U01NR004061, U01AG012505, U01AG012535, U01AG012531, U01AG012539, U01AG012546, U01AG012553, U01AG012554, U01AG012495]
- NATIONAL INSTITUTE OF NURSING RESEARCH [U01NR004061] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [U01AG012531, U01AG012535, U01AG012553, U01AG012495, U01AG012505, U01AG012539, U01AG012554, U01AG012546, K23AG049466] Funding Source: NIH RePORTER
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Key cycle changes occur as women transition from reproductive life to menopause, and they can be roughly linked to menopausal staging. It is important to understand the types of studies that inform the current knowledge. Patterns of symptoms within menstrual cycles (sleep, headache) generally favor worsening in association with the perimenstrual phase of the cycle, and patterns of chronic symptoms, such as hot flashes and adverse mood, appear to be worse when hormones are more variable.
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