4.8 Article

The UCSC Genome Browser database: 2019 update

Journal

NUCLEIC ACIDS RESEARCH
Volume 47, Issue D1, Pages D853-D858

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gky1095

Keywords

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Funding

  1. National Human Genome Research Institute [4U41HG002371, 5U41HG007234, 5U54HG007990]
  2. NIH [1U01MH114825]
  3. California Institute for Regenerative Medicine [GC1R-06673-C]
  4. Howard Hughes Medical Institute [090100]
  5. Regeneron [CBJCHBCAABAA-nBGXMxFrE0WG7VvHOtm8RAzv674WMNt]
  6. St. Baldricks Foundation [427053]
  7. Silicon Valley Community Foundation [2018-182809, 2017-171519]

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The UCSC Genome Browser (https://genome.ucsc.edu) is a graphical viewer for exploring genome annotations. For almost two decades, the Browser has provided visualization tools for genetics and molecular biology and continues to add new data and features. This year, we added a new tool that lets users interactively arrange existing graphing tracks into new groups. Other software additions include new formats for chromosome interactions, a ChIP-Seq peak display for track hubs and improved support for HGVS. On the annotation side, we have added gnomAD, TCGA expression, RefSeq Functional elements, GTEx eQTLs, CRISPR Guides, SNPpedia and created a 30-way primate alignment on the human genome. Nine assemblies now have RefSeq-mapped gene models.

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