Journal
NEW ENGLAND JOURNAL OF MEDICINE
Volume 379, Issue 15, Pages 1452-1462Publisher
MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMra1615014
Keywords
-
Categories
Funding
- NCATS NIH HHS [U24 TR002306] Funding Source: Medline
- NIH HHS [R24 OD011883] Funding Source: Medline
Ask authors/readers for more resources
A GOAL OF PRECISION MEDICINE1 IS TO STRATIFY PATIENTS IN ORDER TO improve diagnosis and medical treatment. Translational investigators are bringing to bear ever greater amounts of heterogeneous clinical data and scientific information to create classification strategies that enable the matching of intervention to underlying mechanisms of disease in subgroups of patients. Ontologies are systematic representations of knowledge that can be used to integrate and analyze large amounts of heterogeneous data, allowing precise classification of a patient. In this review, we describe ontologies and their use in computational reasoning to support precise classification of patients for diagnosis, care management, and translational research.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available