Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 26, Issue 1, Pages 3-13Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41594-018-0166-x
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Funding
- Howard Hughes Medical Institute
- NIH [CA218255]
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Since the first high-resolution structure of the nucleosome was reported in 1997, the available information on chromatin structure has increased very rapidly. Here, we review insights derived from cutting-edge biophysical and structural approaches applied to the study of nucleosome dynamics and nucleosome-binding factors, with a focus on the experimental advances driving the research. In addition, we highlight emerging challenges in nucleosome structural biology.
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