4.7 Editorial Material

STIM1 moonlights as an anchor for STING

Journal

NATURE IMMUNOLOGY
Volume 20, Issue 2, Pages 112-114

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/s41590-018-0300-2

Keywords

-

Categories

Ask authors/readers for more resources

Activation of STING requires its translocation from the endoplasmic reticulum (ER) through the Golgi to vesicles, but the mechanisms that control its localization have been unclear. The ER calcium sensor STIM1 acts as an ER-retention factor that anchors STING on the ER and limits STING signaling.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available