Journal
NATURE CHEMICAL BIOLOGY
Volume 14, Issue 12, Pages 1069-1070Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41589-018-0167-4
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Terpenoids are assembled from five-carbon (C5) units, which limits the available scaffold chemical space for the discovery of bioactive molecules. A combination of enzyme and metabolic engineering now enables biosynthesis of a plethora of non-natural C11 terpenoids.
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