Journal
NATURAL PRODUCT RESEARCH
Volume 34, Issue 17, Pages 2514-2517Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2018.1540476
Keywords
Ficus benjamina; triterpenoids; ursolic acid; lupeol; antiplasmodial activity
Categories
Ask authors/readers for more resources
This study emphasizes on the investigation of antiplasmodial activity of triterpenoids isolated fromFicus benjaminaleaves. An unsaponified fraction of petroleum ether extract of plant leaves was subjected to silica gel column chromatography which led to the isolation of two known triterpenoids; namely ursolic acid and lupeol. These compounds were evaluated for antiplasmodial activity by schizont maturation inhibition assay using 3D7 Plasmodium strains. Both, ursolic acid and lupeol were found to exhibit significant antiplasmodial effect with an IC(50)value of 18 mu g/ml and 3.8 mu g/ml, respectively. This study further confirms the traditional role ofFicus benjaminaplant in the treatment of malaria which may be attributed to ursolic acid and lupeol.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available