Journal
MOLECULES
Volume 23, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/molecules23112851
Keywords
gold nanoshells; gold nanoshell synthesis; cored gold nanoshells; hollow gold nanoshells; template galvanic replacement method
Funding
- Natural Sciences and Engineering Council (NSERC) of Canada
- Fonds de Recherche du Quebec Nature et Technologies (FRQNT, Quebec, Canada)
- Centre for Self-Assembled Chemical Structures (CSACS)
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Gold nanostructures that can be synthetically articulated to adapt diverse morphologies, offer a versatile platform and tunable properties for applications in a variety of areas, including biomedicine and diagnostics. Among several conformational architectures, gold nanoshells provide a highly advantageous combination of properties that can be fine-tuned in designing single or multi-purpose nanomaterials, especially for applications in biology. One of the important parameters for evaluating the efficacy of gold nano-architectures is their reproducible synthesis and surface functionalization with desired moieties. A variety of methods now exist that allow fabrication and chemical manipulation of their structure and resulting properties. This review article provides an overview and a discussion of synthetic methodologies to a diverse range of gold nanoshells, and a brief summary of surface functionalization and characterization methods employed to evaluate their overall composition.
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