Journal
MOLECULES
Volume 23, Issue 12, Pages -Publisher
MDPI
DOI: 10.3390/molecules23123280
Keywords
RTCA; application progress; traditional Chinese medicine; pharmaceutical evaluation
Funding
- National Natural Science Foundation of China [81773910, 81202922, 81603302]
- Jiangsu Provincial Natural Science Foundation of China [BK20150215]
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Objective: We summarized the progress of the xCELLigence real-time cell analysis (RTCA) technology application in recent years for the sake of enriching and developing the application of RTCA in the field of Chinese medicine. Background: The RTCA system is an established electronic cellular biosensor. This system uses micro-electronic biosensor technology that is confirmed for real-time, label-free, dynamic and non-offensive monitoring of cell viability, migration, growth, spreading, and proliferation. Methods: We summarized the relevant experiments and literature of RTCA technology from the principles, characteristics, applications, especially from the latest application progress. Results and conclusion: RTCA is attracting more and more attention. Now it plays an important role in drug screening, toxicology, Chinese herbal medicine and so on. It has wide application prospects in the area of modern pharmaceutical evaluation and analysis.
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