Related references
Note: Only part of the references are listed.Regulation of heat shock transcription factors and their roles in physiology and disease
Rocio Gomez-Pastor et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target
Jacqueline H. L. Fok et al.
CLINICAL CANCER RESEARCH (2018)
Design, synthesis, and biological evaluation of a series of resorcinol-based N-benzyl benzamide derivatives as potent Hsp90 inhibitors
Sun You Park et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells
Alina D. Nikotina et al.
Oncotarget (2018)
HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
Toshiki Kijima et al.
SCIENTIFIC REPORTS (2018)
Gene expression regulation by heat-shock proteins: the cardinal roles of HSF1 and Hsp90
Gisela I. Mazaira et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2018)
Global cancer control: responding to the growing burden, rising costs and inequalities in access
Gerald W. Prager et al.
ESMO OPEN (2018)
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen
Matthew D. Cheeseman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Regulation of the mammalian heat shock factor 1
Sharadha Dayalan Naidu et al.
FEBS JOURNAL (2017)
Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach
Suman Chatterjee et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Ugi Reaction-Derived α-Acyl Aminocarboxamides Bind to Phosphatidylinositol 3-Kinase-Related Kinases, Inhibit HSF1-Dependent Heat Shock Response, and Induce Apoptosis in Multiple Myeloma Cells
Matthias Bach et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
A Pre-Clinical Evaluation of Minnelide in Treating Melanoma
Vrishketan Sethi et al.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2017)
Heat Shock Protein-Inducing Property of Diarylheptanoid Containing Chalcone Moiety from Alpinia katsumadai
Joo-Won Nam et al.
MOLECULES (2017)
New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival
Nuria Vilaboa et al.
NUCLEIC ACIDS RESEARCH (2017)
Rethinking HSF1 in Stress, Development, and Organismal Health
Jian Li et al.
TRENDS IN CELL BIOLOGY (2017)
Selective killing of cancer cells by small molecules targeting heat shock stress response
Daniel Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Targeting the entry region of Hsp90's ATP binding pocket with a novel 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl amide
Ju Hui Jeong et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Heat Shock Factor 1: From Fire Chief to Crowd-Control Specialist
Catherine G. Triandafillou et al.
MOLECULAR CELL (2016)
Structure of human heat-shock transcription factor 1 in complex with DNA
Tobias Neudegger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
HSF1 Guardian of Proteostasis in Cancer
Chengkai Dai et al.
TRENDS IN CELL BIOLOGY (2016)
Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9
Carl S. Rye et al.
MEDCHEMCOMM (2016)
Structure of human heat-shock transcription factor 1 in complex with DNA
Tobias Neudegger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter
Joo Ae Kim et al.
CARCINOGENESIS (2015)
Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis
Sophie Bustany et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2015)
When Cancer Fights Back: Multiple Myeloma, Proteasome Inhibition, and the Heat-Shock Response
Shardule P. Shah et al.
MOLECULAR CANCER RESEARCH (2015)
Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia
Siddhartha Ganguly et al.
ONCOTARGET (2015)
Discovery of hybrid Hsp90 inhibitors and their anti-neoplastic effects against gefitinib-resistant non-small cell lung cancer (NSCLC)
Chul-Ho Jeong et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Pleiotropic Role of HSF1 in Neoplastic Transformation
Natalia Vydra et al.
CURRENT CANCER DRUG TARGETS (2014)
2,4-Bis(4-hydroxybenzyl)phenol Inhibits Heat Shock Transcription Factor 1 and Sensitizes Lung Cancer Cells to Conventional Anticancer Modalities
Taesook Yoon et al.
JOURNAL OF NATURAL PRODUCTS (2014)
Targeting the hydrophobic region of Hsp90's ATP binding pocket with novel 1,3,5-triazines
Taeho Lee et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Heat Shock Factor 1 (HSF1) Controls Chemoresistance and Autophagy through Transcriptional Regulation of Autophagy-related Protein 7 (ATG7)
Shruti Desai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The Natural Compound Cantharidin Induces Cancer Cell Death through Inhibition of Heat Shock Protein 70 (HSP70) and Bcl-2-associated Athanogene Domain 3 (BAG3) Expression by Blocking Heat Shock Factor 1 (HSF1) Binding to Promoters
Joo Ae Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State
Sandro Santagata et al.
SCIENCE (2013)
Small Molecule Activators of the Heat Shock Response: Chemical Properties, Molecular Targets, and Therapeutic Promise
James D. West et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2012)
Post-Translational Modification of Human Heat Shock Factors and Their Functions: A Recent Update by Proteomic Approach
Yan-Ming Xu et al.
JOURNAL OF PROTEOME RESEARCH (2012)
Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms
Zhao-Li Zhou et al.
NATURAL PRODUCT REPORTS (2012)
A Preclinical Evaluation of Minnelide as a Therapeutic Agent Against Pancreatic Cancer
Rohit Chugh et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to the hsp70 Promoter
Young Ju Yoon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Implication of Heat Shock Factors in Tumorigenesis: Therapeutical Potential
Aurelie De Thonel et al.
Cancers (2011)
Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70
Phoebe A. Phillips et al.
CANCER RESEARCH (2007)
Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death
SD Westerheide et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors
N Zaarur et al.
CANCER RESEARCH (2006)
Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status
K Ohnishi et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2004)
Celastrols as inducers of the heat shock response and cytoprotection
SD Westerheide et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetin
PJ Mulholland et al.
ANNALS OF ONCOLOGY (2001)