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Deficiency in neuronal TGF-β signaling promotes neurodegeneratbn and Alzheimer's pathology
Ina Tesseur et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Altered subcellular location of phosphorylated Smads in Alzheimer's disease
Uwe Ueberham et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Astrocytic complexity distinguishes the human brain
Nancy Ann Oberheim et al.
TRENDS IN NEUROSCIENCES (2006)
The logic of TGFβ signaling
Joan Massague et al.
FEBS LETTERS (2006)
Glia-derived D-serine controls NMDA receptor activity and synaptic memory
Aude Panatier et al.
CELL (2006)
Transforming growth factor β2 autocrinally mediates neuronal cell death induced by amyloid-β
Y Hashimoto et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2006)
TGF-β1-induced long-term changes in neuronal excitability in Aplysia sensory neurons depend on MAPK
J Chin et al.
JOURNAL OF NEUROPHYSIOLOGY (2006)
Postsynaptic mad signaling at the Drosophila neuromuscular junction
V Dudu et al.
CURRENT BIOLOGY (2006)
Neural plasticity in the ageing brain
SN Burke et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Astrocyte-endothelial interactions at the blood-brain barrier
NJ Abbott et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Neuronal differentiation in the adult hippocampus recapitulates embryonic development
MS Espósito et al.
JOURNAL OF NEUROSCIENCE (2005)
Vascular development of the brain requires β8 integrin expression in the neuroepithelium
JM Proctor et al.
JOURNAL OF NEUROSCIENCE (2005)
Evidence that embryonic the onset of cortical neurons regulate gliogenesis via cardiotrophin-1
F Barnabé-Heider et al.
NEURON (2005)
Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β:: implications for carcinogenesis
D Javelaud et al.
ONCOGENE (2005)
Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron
C Goritz et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2005)
Integrin αvβ8-mediated activation of transforming growth factor-β by perivascular astrocytes -: An angiogenic control switch
S Cambier et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis
KS Christopherson et al.
CELL (2005)
Selective ablation of alpha v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death
JH McCarty et al.
DEVELOPMENT (2005)
The transforming growth factor-β superfamily of receptors
M de Caestecker
CYTOKINE & GROWTH FACTOR REVIEWS (2004)
Thrombospondin-1 is a major activator of TGF-β in fibrotic renal disease in the rat in vivo
C Daniel et al.
KIDNEY INTERNATIONAL (2004)
Endothelial cell-astrocyte interactions and TGFβ are required for induction of blood-neural barrier properties
CM Garcia et al.
DEVELOPMENTAL BRAIN RESEARCH (2004)
TGF-β induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways
T Nakagawa et al.
KIDNEY INTERNATIONAL (2004)
Role of LRP in TGFβ2-mediated neuronal uptake of Aβ and effects on memory
ME Harris-White et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Glia mediates the neuroprotective action of estradiol on β-amyloid-induced neuronal death
MA Sortino et al.
ENDOCRINOLOGY (2004)
Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system
H Gerhardt et al.
DEVELOPMENTAL DYNAMICS (2004)
Endoglin promotes endothelial cell proliferation and TGF-β/ALK1 signal transduction
F Lebrin et al.
EMBO JOURNAL (2004)
Transforming growth factor-β1 upregulates the tight junction and P-glycoprotein of brain microvascular endothelial cells
S Dohgu et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2004)
Increased plasma levels of soluble CD40, together with the decrease of TGFβ1, as possible differential markers of Alzheimer disease
A Mocali et al.
EXPERIMENTAL GERONTOLOGY (2004)
Loss of TGF-β1 leads to increased neuronal cell death and microgliosis in mouse brain
TC Brionne et al.
NEURON (2003)
Contribution of astrocytes to hippocampal long-term potentiation through released D-serine
YL Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Cerebellar deficits and hyperactivity in mice lacking Smad4
YX Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
New roles for astrocytes: Redefining the functional architecture of the brain
M Nedergaard et al.
TRENDS IN NEUROSCIENCES (2003)
Controlling the angiogenic switch -: A balance between two distinct TGF-β receptor signaling pathways
MJ Goumans et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2003)
Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures
S Koizumi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Radial glia diversity:: A matter of cell fate
AR Kriegstein et al.
GLIA (2003)
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
H Gerhardt et al.
JOURNAL OF CELL BIOLOGY (2003)
Mechanisms of TGF-β signaling from cell membrane to the nucleus
YG Shi et al.
CELL (2003)
Expression of transforming growth factor-β in developing rat cerebral cortex:: Effects of prenatal exposure to ethanol
MW Miller
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Tumorigenesis and the angiogenic switch
G Bergers et al.
NATURE REVIEWS CANCER (2003)
Cortical radial glial cells in human fetuses: Depth-correlated transformation into astrocytes
LC DeAzevedo et al.
JOURNAL OF NEUROBIOLOGY (2003)
Transforming growth factor-β1 potentiates amyloid-β generation in astrocytes and in transgenic mice
S Lesné et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Drosophila neuromuscular synapse assembly and function require the TGF-β type I receptor saxophone and the transcription factor mad
JM Rawson et al.
JOURNAL OF NEUROBIOLOGY (2003)
Neuro-glia interaction effects on GFAP gene:: a novel role for transforming growth factor-β1
TCLDE Spohr et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2002)
Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling
V Colangelo et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Cerebrovascular transforming growth factor-β contributes to inflammation in the Alzheimer's disease brain
P Grammas et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Balancing the activation state of the endothelium via two distinct TGF-β type I receptors
MJ Goumans et al.
EMBO JOURNAL (2002)
Control of synaptic strength by glial TNFα
EC Beattie et al.
SCIENCE (2002)
Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
HW Wang et al.
BRAIN RESEARCH (2002)
Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia
E Tarkowski et al.
NEUROBIOLOGY OF AGING (2002)
TGF-beta and the regulation of neuron survival and death
K Krieglstein et al.
JOURNAL OF PHYSIOLOGY-PARIS (2002)
CNS synaptogenesis promoted by glia-derived cholesterol
DH Mauch et al.
SCIENCE (2001)
TGF-β1 promotes microglial amyloid-β clearance and reduces plaque burden in transgenic mice
T Wyss-Coray et al.
NATURE MEDICINE (2001)
Abnormal angiogenesis but intact hematopoietic potential in TGF-β type I receptor-deficient mice
J Larsson et al.
EMBO JOURNAL (2001)
Inhibition of angiogenesis in vivo by plasminogen activator inhibitor-1
S Stefansson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Control of synapse number by glia
EM Ullian et al.
SCIENCE (2001)
The transforming growth factor-βs:: Structure, signaling, and roles in nervous system development and functions
M Böttner et al.
JOURNAL OF NEUROCHEMISTRY (2000)
Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons
V Parpura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis
SP Oh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Chronic overproduction of transforming growth factor-beta 1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice
T Wyss-Coray et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats
TD Smith et al.
JOURNAL OF NEUROSCIENCE (2000)