Related references
Note: Only part of the references are listed.Cysteine-Rich Repeat Domains 2 and 4 are Amyloid-β Binding Domains of Neurotrophin Receptor p75NTR and Potential Targets to Block Amyloid-β Neurotoxicity
Ye-Ran Wang et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Acute Down-regulation of BDNF Signaling Does Not Replicate Exacerbated Amyloid-β Levels and Cognitive Impairment Induced by Cholinergic Basal Forebrain Lesion
Marion T. Turnbull et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
Cholinergic basal forebrain neurons regulate fear extinction consolidation through p75 neurotrophin receptor signaling
Zoran Boskovic et al.
TRANSLATIONAL PSYCHIATRY (2018)
Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology
Benjamin Kolisnyk et al.
CEREBRAL CORTEX (2017)
Urinary p75ECD A prognostic, disease progression, and pharmacodynamic biomarker in ALS
Stephanie R. Shepheard et al.
NEUROLOGY (2017)
G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channel Activation by the p75 Neurotrophin Receptor Is Required for Amyloid β Toxicity
Linda M. May et al.
FRONTIERS IN NEUROSCIENCE (2017)
Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes
Leah Zuroff et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
Inhibition of motor neuron death in vitro and in vivo by a p75 neurotrophin receptor intracellular domain fragment
Dusan Matusica et al.
JOURNAL OF CELL SCIENCE (2016)
Intramuscular delivery of p75NTR ectodomain by an AAV vector attenuates cognitive deficits and Alzheimer's disease-like pathologies in APP/PS1 transgenic mice
Qing-Hua Wang et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors
Benjamin Kolisnyk et al.
JOURNAL OF NEUROSCIENCE (2016)
Cognitive deficits are ameliorated by reduction in amyloid β accumulation in Tg2576/p75NTR+/- mice
Chongdong Jian et al.
LIFE SCIENCES (2016)
Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease
Weiguo Peng et al.
NEUROBIOLOGY OF DISEASE (2016)
Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology
Taylor W. Schmitz et al.
NATURE COMMUNICATIONS (2016)
p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer's disease
X-Q Yao et al.
MOLECULAR PSYCHIATRY (2015)
Reduction of p75 neurotrophin receptor ameliorates the cognitive deficits in a model of Alzheimer's disease
Mark Murphy et al.
NEUROBIOLOGY OF AGING (2015)
Basal forebrain atrophy contributes to allocentric navigation impairment in alzheimer's disease patients
Georg M. Kerbler et al.
FRONTIERS IN AGING NEUROSCIENCE (2015)
Differential levels of p75NTR ectodomain in CSF and blood in patients with Alzheimer's disease: a novel diagnostic marker
S-S Jiao et al.
TRANSLATIONAL PSYCHIATRY (2015)
Basal forebrain atrophy correlates with amyloid beta burden in Alzheimer's disease
Georg M. Kerbler et al.
NEUROIMAGE-CLINICAL (2015)
Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects
Michel J. Grothe et al.
ALZHEIMERS & DEMENTIA (2014)
Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons
Saak V. Ovsepian et al.
BRAIN STRUCTURE & FUNCTION (2014)
Getting Rid of Intracellular Aβ - Loss of Cellular Degradation Leads to Transfer Between Connected Neurons
Lotta Agholme et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
Small Molecule p75(NTR) Ligands Reduce Pathological Phosphorylation and Misfolding of Tau, Inflammatory Changes, Cholinergic Degeneration, and Cognitive Deficits in A beta PPL/S Transgenic Mice
Thuy-Vi V. Nguyen et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Atrophy of the cholinergic basal forebrain in dementia with Lewy bodies and Alzheimer's disease dementia
Michel J. Grothe et al.
JOURNAL OF NEUROLOGY (2014)
The Role of p75NTR in Cholinergic Basal Forebrain Structure and Function
Zoran Boskovic et al.
JOURNAL OF NEUROSCIENCE (2014)
Cholinergic basal forebrain atrophy predicts amyloid burden in Alzheimer's disease
Stefan Teipel et al.
NEUROBIOLOGY OF AGING (2014)
Immunolesion-induced loss of cholinergic projection neurones promotes β-amyloidosis and tau hyperphosphorylation in the hippocampus of triple-transgenic mice
W. Haertig et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2014)
The Extracellular Domain of Neurotrophin Receptor p75 as a Candidate Biomarker for Amyotrophic Lateral Sclerosis
Stephanie R. Shepheard et al.
PLOS ONE (2014)
Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice
Bettina Laursen et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Rapid β-Amyloid Deposition and Cognitive Impairment After Cholinergic Denervation in APP/PS1 Mice
Juan Jose Ramos-Rodriguez et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2013)
Immature Doublecortin-Positive Hippocampal Neurons Are Important for Learning But Not for Remembering
Jana Vukovic et al.
JOURNAL OF NEUROSCIENCE (2013)
Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease
Frank M. Longo et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease
Michel Grothe et al.
NEUROBIOLOGY OF AGING (2013)
Drain of the brain: low-affinity p75 neurotrophin receptor affords a molecular sink for clearance of cortical amyloid β by the cholinergic modulator system
Saak V. Ovsepian et al.
NEUROBIOLOGY OF AGING (2013)
A small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model
Juliet K. Knowles et al.
NEUROBIOLOGY OF AGING (2013)
Lesions of the Basal Forebrain Cholinergic System in Mice Disrupt Idiothetic Navigation
Adam S. Hamlin et al.
PLOS ONE (2013)
A DR6/p75NTR complex is responsible for β-amyloid-induced cortical neuron death
Y. Hu et al.
CELL DEATH & DISEASE (2013)
Cholinergic control of the cerebral vasculature in humans
J. W. Hamner et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice
Francisco J. Gil-Bea et al.
NEUROBIOLOGY OF DISEASE (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity
Carlos F. Ibanez et al.
TRENDS IN NEUROSCIENCES (2012)
Microglia function in Alzheimer's disease
Egle Solito et al.
FRONTIERS IN PHARMACOLOGY (2012)
Roles of p75NTR in the pathogenesis of Alzheimer's disease: A novel therapeutic target
Fan Zeng et al.
BIOCHEMICAL PHARMACOLOGY (2011)
The Cholinergic System in Mild Cognitive Impairment and Alzheimer's Disease: An In Vivo MRI and DTI study
Stefan J. Teipel et al.
HUMAN BRAIN MAPPING (2011)
p75NTR Regulates Aβ Deposition by Increasing Aβ Production But Inhibiting Aβ Aggregation with Its Extracellular Domain
Yan-Jiang Wang et al.
JOURNAL OF NEUROSCIENCE (2011)
The p75NTR extracellular domain A potential molecule regulating the solubility and removal of amyloid-β
Xin-Fu Zhou et al.
PRION (2011)
Reduction of Basal Forebrain Cholinergic System Parallels Cognitive Impairment in Patients at High Risk of Developing Alzheimer's Disease
Michel Grothe et al.
CEREBRAL CORTEX (2010)
Amyloid-beta Peptides Stimulate the Expression of the p75(NTR) Neurotrophin Receptor in SH-SY5Y Human Neuroblastoma Cells and AD Transgenic Mice
Balu Chakravarthy et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo
Albert A. Davis et al.
JOURNAL OF NEUROSCIENCE (2010)
Loss of α7 Nicotinic Receptors Enhances β-Amyloid Oligomer Accumulation, Exacerbating Early-Stage Cognitive Decline and Septohippocampal Pathology in a Mouse Model of Alzheimer's Disease
Caterina M. Hernandez et al.
JOURNAL OF NEUROSCIENCE (2010)
Circulating neprilysin clears brain amyloid
Yinxing Liu et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2010)
The p75 Neurotrophin Receptor Promotes Amyloid-β(1-42)-Induced Neuritic Dystrophy In Vitro and In Vivo
Juliet K. Knowles et al.
JOURNAL OF NEUROSCIENCE (2009)
The Role of the p75 Neurotrophin Receptor in Cholinergic Dysfunction in Alzheimer's Disease
E. J. Coulson et al.
NEUROSCIENTIST (2009)
The p75 neurotrophin receptor regulates hippocampal neurogenesis and related behaviours
Vibeke S. Catts et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications
Elliott J Mufson et al.
Expert Review of Neurotherapeutics (2008)
β-amyloid1-42 induces neuronal death through the p75 neurotrophin receptor
Areechun Sotthibundhu et al.
JOURNAL OF NEUROSCIENCE (2008)
Small Molecule, Non-Peptide p75NTR Ligands Inhibit Aβ-Induced Neurodegeneration and Synaptic Impairment
Tao Yang et al.
PLOS ONE (2008)
M1 receptors play a central role in modulating AD-like pathology in transgenic mice
A Caccamo et al.
NEURON (2006)
Activation of p75NTR by proBDNF facilitates hippocampal long-term depression
NH Woo et al.
NATURE NEUROSCIENCE (2005)
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus
H Rösch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Beyond memory, navigation, and inhibition: Behavioral evidence for hippocampus-dependent cognitive coordination in the rat
M Wesierska et al.
JOURNAL OF NEUROSCIENCE (2005)
Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in beta-amyloid peptide-dependent cell death
C Costantini et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2005)
The neurotrophin receptor p75NTR:: novel functions and implications for diseases of the nervous system
G Dechant et al.
NATURE NEUROSCIENCE (2002)
Role of p75 neurotrophin receptor in the neurotoxicity by β-amyloid peptides and synergistic effect of inflammatory cytokines
G Perini et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Amyloid β binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling
M Yaar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Loss of basal Forebrain p75NTR immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease
EJ Mufson et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2002)
Neuropathology of mice carrying mutant APPswe and/or PS1M146L transgenes:: Alterations in the p75NTR cholinergic basal forebrain septohippocampal pathway
S Jaffar et al.
EXPERIMENTAL NEUROLOGY (2000)
Passive and active place avoidance as a tool of spatial memory research in rats
JM Cimadevilla et al.
JOURNAL OF NEUROSCIENCE METHODS (2000)
High-level neuronal expression of Aβ1-42 in wild-type human amyloid protein precursor transgenic mice:: Synaptotoxicity without plaque formation
L Mucke et al.
JOURNAL OF NEUROSCIENCE (2000)
Enlarged cholinergic forebrain neurons and improved spatial learning in p75 knockout mice
U Greferath et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2000)
Share Paper
