4.6 Review

Deep learning in medical imaging and radiation therapy

Journal

MEDICAL PHYSICS
Volume 46, Issue 1, Pages e1-e36

Publisher

WILEY
DOI: 10.1002/mp.13264

Keywords

computer-aided detection/characterization; deep learning, machine learning; reconstruction; segmentation; treatment

Funding

  1. NIH [CA 195564, CA 166945, CA 189240]
  2. University of Chicago [CTSA UL1 TR000430]
  3. U.S. Food and Drug Administration
  4. Intramural Research Programs of the NIH Clinical Center
  5. NATIONAL CANCER INSTITUTE [U01CA195564] Funding Source: NIH RePORTER
  6. CLINICAL CENTER [ZIACL040004] Funding Source: NIH RePORTER

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The goals of this review paper on deep learning (DL) in medical imaging and radiation therapy are to (a) summarize what has been achieved to date; (b) identify common and unique challenges, and strategies that researchers have taken to address these challenges; and (c) identify some of the promising avenues for the future both in terms of applications as well as technical innovations. We introduce the general principles of DL and convolutional neural networks, survey five major areas of application of DL in medical imaging and radiation therapy, identify common themes, discuss methods for dataset expansion, and conclude by summarizing lessons learned, remaining challenges, and future directions.

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