Journal
MARINE DRUGS
Volume 16, Issue 12, Pages -Publisher
MDPI
DOI: 10.3390/md16120509
Keywords
echinochrome A; composition of antioxidants; antioxidant activity; antiviral activity
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Funding
- Ministry of Science and Education of the Russian Federation [RFMEF161317X0076]
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The aim of this study was to examine the in vitro antioxidant and antiviral activities of echinochrome A and echinochrome-based antioxidant composition against tick-borne encephalitis virus (TBEV) and herpes simplex virus type 1 (HSV-1). The antioxidant composition, which is a mixture of echinochrome A, ascorbic acid, and -tocopherol (5:5:1), showed higher antioxidant and antiviral effects than echinochrome A. We suppose that echinochrome A and its composition can both directly affect virus particles and indirectly enhance antioxidant defense mechanisms in the hosting cell. The obtained results allow considering the echinochrome A and the composition of antioxidants on its basis as the promising agents with the both antioxidant and antiviral activities.
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