Journal
LIPIDS
Volume 53, Issue 11-12, Pages 1019-1020Publisher
WILEY
DOI: 10.1002/lipd.12111
Keywords
Lipid analysis; Lipid chemistry; Mass spectrometry (MS); Phospholipid analysis
Funding
- Kansas INBRE
- National Institute of General Medical Sciences of the National Institutes of Health
- NIH [P20GM103418, P20GM113117]
- Chemical Biology of Infectious Disease Centers of Biomedical Research Excellence (COBRE)
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LipidomeDB Data Calculation Environment (DCE), a web application for processing data from direct-infusion tandem mass spectrometer data on lipids, was described by Zhou et al. (, Lipids, 46, 879-884). The original version processed multiple precursor and/or neutral loss scans on multiple samples. A recent update to LipidomeDB DCE, , extends LipidomeDB DCE's functionality to process data acquired in multiple reaction monitoring (MRM) mode by direct-infusion mass spectrometry. Both the precursor-neutral loss workflow and the MRM workflow remove signals due to isotopic overlap of lipid analytes and calculation of the amount of each target lipid in comparison with internal standards.
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