Journal
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 16, Issue 6, Pages 1139-1146Publisher
SPRINGER
DOI: 10.1007/s13738-018-01589-9
Keywords
Multicomponent reactions; Spiro compounds; Synthetic methods; Cyclization
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Funding
- University of Isfahan research council
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A series of 4-amino-functionalized spiropyrimidine-2-thione derivatives were simply produced by the one-pot three-component reaction of alicyclic carbonyl compounds, nitriles containing an acidic methylene, and thiourea in the presence of NaOMe in MeOH.
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