Journal
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 16, Issue 2, Pages 355-363Publisher
SPRINGER
DOI: 10.1007/s13738-018-1518-5
Keywords
Green synthesis; Carbon dots; Penicillamine; Fluorimetric sensor; Inner filter effect
Categories
Ask authors/readers for more resources
In the present work, an optical sensor for quantitative measurement of penicillamine (PA) was fabricated. In this optical sensor, carbon dots (CDs), which were synthesized from saffron, were used as a fluorophore. This fluorophore exhibited high fluorescence and stability in various medium. The emission light of the CDs could be absorbed by PA-Cu(II) complex via inner filter effect. This fluorescence intensity reducing was proportional to the concentration of PA in a constant concentration of Cu(II) and could be applied as an analytical signal for PA determination in the range of 0.05-13.0 mu g/mL with a detection limit as 0.02 mu g/mL. Under the optimum conditions, 0.5 and 9.0 mu g/mL of PA solutions were measured five times, and the results showed an RSD% of 1.9% and 2.3%, respectively. Finally, the suggested optical sensor was fruitfully used for PA measurement in human plasma samples.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available