Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 141, Issue 1, Pages 25-28Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jacs.8b10212
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Funding
- Baylor University
- Welch Foundation [AA-006]
- Cancer Prevention and Research Institute of Texas (CPRIT) [R1309]
- NSF [CHE-1764240]
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The total syntheses of (-)-herquline B (2) and a heretofore-unrecognized congener, (+)-herquline C (3), are described. The syntheses require 14 and 13 steps, respectively, and feature a key oxazoline reduction that sets the stage for piperazine construction.
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