Journal
BIOCHEMISTRY-MOSCOW
Volume 80, Issue 13, Pages 1723-1733Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0006297915130088
Keywords
zebrafish; ZGA; MBT; pluripotency; Oct4; Nanog
Categories
Funding
- Deutsche Forschungsgemeinschaft [ON86/3-1]
- Russian Foundation for Basic Research [14-54-12008]
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Events, manifesting transition from maternal to zygotic period of development are studied for more than 100 years, but underlying mechanisms are not yet clear. We provide a brief historical overview of development of concepts and explain the specific terminology used in the field. We further discuss differences and similarities between the zygotic genome activation and in vitro reprogramming process. Finally, we envision the future research directions within the field, where biochemical methods will play increasingly important role.
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