Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 84, Issue 4, Pages 2039-2047Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.8b03048
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Funding
- CSIR, New Delhi
- UGC
- Department of Science and Technology DST
- DST [EMR/2014/000013]
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A highly regioselective, efficient, and metal-free oxidative cross dehydrogenative coupling (CDC) of aryl carbonyls with cyclic ethers has been developed. This method offers easy access to substituted alpha-arylated cyclic ethers with a high functional group tolerance in good to excellent yields. The regioselectivity of this CDC reaction was confirmed by density functional theory (DFT)-based calculations.
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