Synthesis of O-1-O-6 Substituted Positional Isomers of D-Glucose-Thioether Ligands and Their Ruthenium Polypyridyl Conjugates

A library of positional isomers of n-glucose (O-1-O-6) as ligands and their 11 light-active ruthenium conjugates has been synthesized. A protecting group strategy without the necessity of using palladium on carbon for the modification for the 2-O and 4-O position allows for the incorporation of sulfur donor atoms as ligands for transition metal complexes.