4.7 Article

More than Just a Motor: Recent Surprises from the Frontal Cortex

Journal

JOURNAL OF NEUROSCIENCE
Volume 38, Issue 44, Pages 9402-9413

Publisher

SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.1671-18.2018

Keywords

motor control; active sensing; action selection; action timing; decision-making; frontal cortex

Categories

Funding

  1. Novo Nordisk Foundation
  2. NYU Provost's Postdoctoral Fellowship
  3. NIDCD K99/R00 Pathway to Independence Award [DC015543-01A1]
  4. NIH HHS/USA [F32 MH098572/MH/NIMH]
  5. Howard Hughes Medical Institute/USA
  6. Uehara Memorial Foundation
  7. Fundacao Bial [127/08]
  8. Fundacao para a Ciencia e a Tecnologia [SFRH/BPD/46314/2008]
  9. JSPS KAKENHI Grant [JP18J01678, JP17K12703]
  10. Program of Shanghai Academic/Technology Research Leader [15XD1503000]
  11. Science and Technology Commission of Shanghai Municipality [15JC1400104]
  12. Fundação para a Ciência e a Tecnologia [SFRH/BPD/46314/2008] Funding Source: FCT

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Motor and premotor cortices are crucial for the control of movements. However, we still know little about how these areas contribute to higher-order motor control, such as deciding which movements to make and when to make them. Here we focus on rodent studies and review recent findings, which suggest that-in addition to motor control-neurons in motor cortices play a role in sensory integration, behavioral strategizing, working memory, and decision-making. We suggest that these seemingly disparate functions may subserve an evolutionarily conserved role in sensorimotor cognition and that further study of rodent motor cortices could make a major contribution to our understanding of the evolution and function of the mammalian frontal cortex.

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