Journal
JOURNAL OF NANOMATERIALS
Volume 2018, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2018/4218270
Keywords
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Funding
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior-Brasil (CAPES) [001]
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico [113844/2018-2]
- MCTI/SisNANO
- RedeAgroNano (Embrapa)
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In this study, the preparation of porous nanocomposite scaffolds (HX-CNT) from a combination of a hydroxamic derivative of alginate (HX) and an amine-functionalized multiwalled carbon nanotube (CNT) at different concentrations is described. The structure of HX was investigated by FTIR, and the degree of substitution around 9% was confirmed by elemental analysis. The interaction between CNT and alginate derivative in the nanocomposite crosslinked with calcium was confirmed by FTIR, Raman spectroscopy, and SEM. The results obtained in this study showed that scaffolds based on HX-CNT composites with a 4wt% concentration level exhibited improved physical and mechanical properties compared to plain alginate (Young's modulus increased from 2.2 to 5.1MPa and elastic strength from 0.13 to 0.25MPa) and decreased the swelling ratios from 900 to 673. The cytotoxicity assays using the L929 cell line proved that the nanocomposite scaffolds were nontoxic, even at the highest CNT concentration.
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