4.7 Article

Trapped and non-trapped polymer translocations through a spherical pore

Journal

JOURNAL OF CHEMICAL PHYSICS
Volume 150, Issue 2, Pages -

Publisher

AMER INST PHYSICS
DOI: 10.1063/1.5063331

Keywords

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Funding

  1. National Natural Science Foundation of China [11704333, 11674277]
  2. Natural Science Foundation of Zhejiang Province [LY16A050004]

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The polymer translocation through a spherical pore is studied using the Langevin dynamics simulation. The translocation events are classified into two types: one is the trapped translocation in which the entire polymer is trapped in the pore and the other is the non-trapped translocation where the pore cannot hold the whole polymer. We find that the trapped translocation is favored at large spheres and small external voltages. However, the monomer-pore attraction would lead to the non-monotonic behavior of the trapped translocation possibility out of all translocation events. Moreover, both the trapped and non-trapped translocation times are dependent on the polymer length, pore size, external voltage, and the monomer-pore attraction. There exist two pathways for the polymer in the trapped translocation: an actively trapped pathway for the polymer trapped in the pore before the head monomer arrives at the pore exit, and a passively trapped pathway for the polymer trapped in the pore while the head monomer is struggling to move out of the pore. The studies of trapped pathways can provide a deep understanding of the polymer translocation behavior. Published under license by AIP Publishing.

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