Journal
JOURNAL OF CELLULAR BIOCHEMISTRY
Volume 120, Issue 3, Pages 2721-2725Publisher
WILEY
DOI: 10.1002/jcb.27690
Keywords
attomolar; Cas13a; clustered regularly interspaced short palindromic repeats-based diagnostic; epidemic diseases; guide-RNA; multiplex
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Funding
- Puri Foundation for Education in India
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The CRISPR-Cas system is a key technology for genome editing and regulation in a wide range of organisms and cell types. Recently, CRISPR-Cas-based diagnostic platform has shown idealistic properties for pathogen detection. Integrating the CRISPR-Cas platform along with lateral flow system allows rapid, sensitive, specific, cheap, and reliable diagnostic. It has the potential to be in frontline for not only pathogen detection during the epidemic outbreak, but also cancer, and genetic diseases.
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