Related references
Note: Only part of the references are listed.Chemical probes and drug leads from advances in synthetic planning and methodology
Christopher J. Gerry et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Small-Molecule Kinase Downregulators
Lyn H. Jones
CELL CHEMICAL BIOLOGY (2018)
Selective degradation of splicing factor CAPERα by anticancer sulfonamides
Taisuke Uehara et al.
NATURE CHEMICAL BIOLOGY (2017)
Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease
Elizaveta S. Leshchiner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer
Liron Bar-Peled et al.
CELL (2017)
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Philipp M. Cromm et al.
CELL CHEMICAL BIOLOGY (2017)
Ligand and Target Discovery by Fragment-Based Screening in Human Cells
Christopher G. Parker et al.
CELL (2017)
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics
Luc de Waal et al.
NATURE CHEMICAL BIOLOGY (2016)
A Novel Destabilizing Domain Based on a Small-Molecule Dependent Fluorophore
Raul Navarro et al.
ACS CHEMICAL BIOLOGY (2016)
Chemical Space of DNA-Encoded Libraries
Raphael M. Franzini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events
Marc S. Sabatine et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Phthalimide conjugation as a strategy for in vivo target protein degradation
Georg E. Winter et al.
SCIENCE (2015)
Designed abscisic acid analogs as antagonists of PYL-PP2C receptor interactions
Jun Takeuchi et al.
NATURE CHEMICAL BIOLOGY (2014)
Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
Jan Kroenke et al.
SCIENCE (2014)
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
Gang Lu et al.
SCIENCE (2014)
Validating therapeutic targets through human genetics
Robert M. Plenge et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
Daniel Martinez Molina et al.
SCIENCE (2013)
Forum Drug discovery A question of library design
Philip J. Hajduk
NATURE (2011)
Dynamics of GBF1, a brefeldin A-sensitive Arf1 exchange factor at the Golgi
TK Niu et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions
RT Peterson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis
SJ Haggarty et al.
CHEMISTRY & BIOLOGY (2000)