Related references
Note: Only part of the references are listed.Overexpression of Flap Endonuclease 1 Correlates with Enhanced Proliferation and Poor Prognosis of Non-Small-Cell Lung Cancer
Keqiang Zhang et al.
AMERICAN JOURNAL OF PATHOLOGY (2018)
Coordinated Activity of Y Family TLS Polymerases and EXO1 Protects Non-S Phase Cells from UV-Induced Cytotoxic Lesions
Sarah Sertic et al.
MOLECULAR CELL (2018)
Missed cleavage opportunities by FEN1 lead to Okazaki fragment maturation via the long-flap pathway
Manal S. Zaher et al.
NUCLEIC ACIDS RESEARCH (2018)
Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners
Eva M. Goellner et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
EXO1 overexpression is associated with poor prognosis of hepatocellular carcinoma patients
Yaoyao Dai et al.
CELL CYCLE (2018)
Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease ensemble in the processing of DNA-bound obstacles
Weibin Wang et al.
GENES & DEVELOPMENT (2017)
Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks
Hyun-Suk Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
DNA mismatch repair and its many roles in eukaryotic cells
Dekang Liu et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2017)
Monogenic Diseases of DNA Repair
Guido Keijzers et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Human DNA polymerase delta double-mutant D316A; E318A interferes with DNA mismatch repair in vitro
Dekang Liu et al.
NUCLEIC ACIDS RESEARCH (2017)
Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLa activation and function in mismatch repair
Jochen Genschel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Expression signatures of DNA repair genes correlate with survival prognosis of astrocytoma patients
Juliana Ferreira de Sousa et al.
TUMOR BIOLOGY (2017)
Significant association of the EXO1 rs851797 polymorphism with clinical outcome of ovarian cancer
Tingyan Shi et al.
ONCOTARGETS AND THERAPY (2017)
Non-homologous end joining: Common interaction sites and exchange of multiple factors in the DNA repair process
Stuart L. Rulten et al.
BIOESSAYS (2017)
Bloom's Syndrome: Clinical Spectrum, Molecular Pathogenesis, and Cancer Predisposition
Christopher Cunniff et al.
MOLECULAR SYNDROMOLOGY (2017)
Exonuclease 1 and its versatile roles in DNA repair
Guido Keijzers et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)
The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on, hard to remove
Birthe B. Kragelund et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2016)
WRN regulates pathway choice between classical and alternative non-homologous end joining
Raghavendra A. Shamanna et al.
Nature Communications (2016)
Associations between Nine Polymorphisms in EXO1 and Cancer Susceptibility: A Systematic Review and Meta-Analysis of 39 Case-control Studies
Meng Zhang et al.
SCIENTIFIC REPORTS (2016)
Human exonuclease 1 (EXO1) activity characterization and its function on flap structures
Guido Keijzers et al.
BIOSCIENCE REPORTS (2015)
Candidate gene analysis of BRCA1/2 mutation-negative high-risk Russian breast cancer patients
Anna P. Sokolenko et al.
CANCER LETTERS (2015)
Catalytic Strand Separation by RECQ1 Is Required for RPA-Mediated Response to Replication Stress
Taraswi Banerjee et al.
CURRENT BIOLOGY (2015)
Poly(ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities
Abigael Cheruiyot et al.
DNA REPAIR (2015)
A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine
Maren F. Hansen et al.
FAMILIAL CANCER (2015)
14-3-3 Proteins Restrain the Exo1 Nuclease to Prevent Overresection
Xiaoqing Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
Kyriaki Michailidou et al.
NATURE GENETICS (2015)
The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks
Greg H. P. Ngo et al.
NUCLEIC ACIDS RESEARCH (2015)
The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation
Chiara Iannascoli et al.
NUCLEIC ACIDS RESEARCH (2015)
The Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replication
Maryna Levikova et al.
NUCLEIC ACIDS RESEARCH (2015)
EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele
Katrin Rein et al.
NUCLEIC ACIDS RESEARCH (2015)
The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response
Feng Zhang et al.
NUCLEIC ACIDS RESEARCH (2015)
The role of RecQ helicases in non-homologous end-joining
Guido Keijzers et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2014)
Exo1 independent DNA mismatch repair involves multiple compensatory nucleases
Amar Desai et al.
DNA REPAIR (2014)
Novel Function of the Fanconi Anemia Group J or RECQ1 Helicase to Disrupt Protein-DNA Complexes in a Replication Protein A-stimulated Manner
Joshua A. Sommers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
PCNA and Msh2-Msh6 Activate an Mlh1-Pms1 Endonuclease Pathway Required for Exo1-Independent Mismatch Repair
Eva M. Goellner et al.
MOLECULAR CELL (2014)
Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer
Tarek M. A. Abdel-Fatah et al.
MOLECULAR ONCOLOGY (2014)
Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1
Stephanie Bregenhorn et al.
NUCLEIC ACIDS RESEARCH (2014)
Hydrolytic function of Exo1 in mammalian mismatch repair
Hongbing Shao et al.
NUCLEIC ACIDS RESEARCH (2014)
The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1
Greg H. P. Ngo et al.
NUCLEIC ACIDS RESEARCH (2014)
The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1
Soo-Hyun Yang et al.
EMBO JOURNAL (2013)
Noncanonical Role of the 9-1-1 Clamp in the Error-Free DNA Damage Tolerance Pathway
Georgios Ioannis Karras et al.
MOLECULAR CELL (2013)
RPA Coordinates DNA End Resection and Prevents Formation of DNA Hairpins
Huan Chen et al.
MOLECULAR CELL (2013)
PCNA promotes processive DNA end resection by Exo1
Xiaoqing Chen et al.
NUCLEIC ACIDS RESEARCH (2013)
Breast Tumors with Elevated Expression of 1q Candidate Genes Confer Poor Clinical Outcome and Sensitivity to Ras/PI3K Inhibition
Muthulakshmi Muthuswami et al.
PLOS ONE (2013)
Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes
Sonja Schaetzlein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Dominant Mutations in S. cerevisiae PMS1 Identify the Mlh1-Pms1 Endonuclease Active Site and an Exonuclease 1-Independent Mismatch Repair Pathway
Catherine E. Smith et al.
PLOS GENETICS (2013)
14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif
Sofie Dabros Andersen et al.
DNA REPAIR (2012)
The Trans-autostimulatory Activity of Rad27 Suppresses dna2 Defects in Okazaki Fragment Processing
Palinda Ruvan Munashingha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Okazaki Fragment Processing-independent Role for Human Dna2 Enzyme during DNA Replication
Julien P. Duxin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Role of MRE11 in Cell Proliferation, Tumor Invasion, and DNA Repair in Breast Cancer
Shyng-Shiou F. Yuan et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2012)
The significance of Exonuclease 1 K589E polymorphism on hepatocellular carcinoma susceptibility in the Turkish population: a case-control study
Suleyman Bayram et al.
MOLECULAR BIOLOGY REPORTS (2012)
RNase H2-Initiated Ribonucleotide Excision Repair
Justin L. Sparks et al.
MOLECULAR CELL (2012)
Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1
Jason W. Gloor et al.
NUCLEIC ACIDS RESEARCH (2012)
Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
Sascha E. Liberti et al.
DNA REPAIR (2011)
PARP-1 enhances the mismatch-dependence of 5'-directed excision in human mismatch repair in vitro
Yiyong Liu et al.
DNA REPAIR (2011)
Genetic polymorphisms in DNA repair and oxidative stress pathways associated with malignant melanoma susceptibility
Maider Ibarrola-Villava et al.
EUROPEAN JOURNAL OF CANCER (2011)
BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
Amitabh V. Nimonkar et al.
GENES & DEVELOPMENT (2011)
Molecular Cooperation between the Werner Syndrome Protein and Replication Protein A in Relation to Replication Fork Blockage
Amrita Machwe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
DNA Mismatch Repair Gene Polymorphisms Affect Survival in Pancreatic Cancer
Xiaoqun Dong et al.
ONCOLOGIST (2011)
14-3-3 Proteins Regulate Exonuclease 1-Dependent Processing of Stalled Replication Forks
Kim Engels et al.
PLOS GENETICS (2011)
Delineation of WRN helicase function with EXO1 in the replicational stress response
Monika Aggarwal et al.
DNA REPAIR (2010)
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
Eun Yong Shim et al.
EMBO JOURNAL (2010)
DNA end resection by CtIP and exonuclease 1 prevents genomic instability
Wassim Eid et al.
EMBO REPORTS (2010)
Impact of EXO1 Polymorphism in Susceptibility to Colorectal Cancer
Mahdi Montazer Haghighi et al.
GENETIC TESTING AND MOLECULAR BIOMARKERS (2010)
An Alternative Pathway for Okazaki Fragment Processing RESOLUTION OF FOLD-BACK FLAPS BY Pif1 HELICASE
Jason E. Pike et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Exo1 Competes with Repair Synthesis, Converts NER Intermediates to Long ssDNA Gaps, and Promotes Checkpoint Activation
Michele Giannattasio et al.
MOLECULAR CELL (2010)
Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions
Kseniya Zakharyevich et al.
MOLECULAR CELL (2010)
Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions
Amy Marie et al.
NUCLEIC ACIDS RESEARCH (2010)
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
Emma Bolderson et al.
NUCLEIC ACIDS RESEARCH (2010)
Single-Nucleotide Polymorphism of the Exo1 Gene: Association with Gastric Cancer Susceptibility and Interaction with Smoking in Taiwan
Da-Tian Bau et al.
CHINESE JOURNAL OF PHYSIOLOGY (2009)
Interaction of Exo1 genotypes and smoking habit in oral cancer in Taiwan
Ming-Hsui Tsai et al.
ORAL ONCOLOGY (2009)
Ctp1 and Exonuclease 1, alternative nucleases regulated by the MRN complex, are required for efficient meiotic recombination
Joseph A. Farah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
Farid A. Kadyrov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks
Monica Segurado et al.
GENES & DEVELOPMENT (2008)
Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal
Marie L. Rossi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Flexibility of Eukaryotic Okazaki Fragment Maturation through Regulated Strand Displacement Synthesis
Carrie M. Stith et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population:: A case-control analysis*
Guangfu Jin et al.
LUNG CANCER (2008)
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
Eleni P. Mimitou et al.
NATURE (2008)
DNA mismatch repair: Molecular mechanism, cancer, and ageing
Peggy Hsieh et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2008)
WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer
Takako Kawasaki et al.
MODERN PATHOLOGY (2008)
ATR-dependent pathways control hEXO1 stability in response to stalled forks
Mahmoud El-Shemerly et al.
NUCLEIC ACIDS RESEARCH (2008)
A mutation in EXO1 defines separable roles in DNA mismatch repair and post-replication repair
Phuoc T. Tran et al.
DNA REPAIR (2007)
Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors
Nurten Saydam et al.
NUCLEIC ACIDS RESEARCH (2007)
Genes overexpressed in different human solid cancers exhibit different tissue-specific expression profiles
Jacob Bock-Axelsen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Reconstituted Okazaki fragment processing indicates two pathways of primer removal
Marie L. Rossi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Physical and functional mapping of the replication protein A interaction domain of the Werner and Bloom syndrome helicases
KM Doherty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination
KM Doherty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice
YX Wang et al.
NATURE GENETICS (2005)
P53 Modulates RPA-dependent and RPA-independent WRN helicase activity
JA Sommers et al.
CANCER RESEARCH (2005)
Single nucleotide polymorphisms in the EXO1 gene and risk of colorectal cancer in a Japanese population
H Yamamoto et al.
CARCINOGENESIS (2005)
Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells
C Cotta-Ramusino et al.
MOLECULAR CELL (2005)
Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA
FC Nielsen et al.
ONCOGENE (2004)
The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks
B Llorente et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The Bloom's syndrome helicase interacts directly with the human DNA mismatch repair protein hMSH6
G Pedrazzi et al.
BIOLOGICAL CHEMISTRY (2003)
The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein
S Sharma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mechanism of 5 '-directed excision in human mismatch repair
J Genschel et al.
MOLECULAR CELL (2003)
A murine model of Nijmegen breakage syndrome
BR Williams et al.
CURRENT BIOLOGY (2002)
Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1
G Pedrazzi et al.
NUCLEIC ACIDS RESEARCH (2001)
How nucleotide excision repair protects against cancer
EC Friedberg
NATURE REVIEWS CANCER (2001)
The interaction of DNA mismatch repair proteins with human exonuclease I
C Schmutte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair
G Langland et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
exo1-Dependent mutator mutations:: Model system for studying functional interactions in mismatch repair
NS Amin et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLα and hMLH1-hEXO1 complexes
AC Jäger et al.
ONCOGENE (2001)
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest
A Constantinou et al.
EMBO REPORTS (2000)
Share Paper
