4.7 Review

Iron Metabolism in Cancer

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

NEET Proteins: A New Link Between Iron Metabolism, Reactive Oxygen Species, and Cancer

Ron Mittler et al.

ANTIOXIDANTS & REDOX SIGNALING (2019)

Review Biochemistry & Molecular Biology

The tumor suppressor protein p53 and the ferroptosis network

Rui Kang et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Biochemistry & Molecular Biology

Role of GPX4 in ferroptosis and its pharmacological implication

Tobias M. Seibt et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Biochemistry & Molecular Biology

Non-transferrin-bound iron transporters

Mitchell D. Knutson

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Article Cell Biology

Ferrosenescence: The iron age of neurodegeneration?

Adonis Sfera et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2018)

Article Biochemistry & Molecular Biology

A FTH1 gene: pseudogene: microRNA network regulates tumorigenesis in prostate cancer

Jia Jia Chan et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Multidisciplinary Sciences

Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells

Colin H. Lipper et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Engineering, Biomedical

Iron Oxide Nanoparticles: Innovative Tool in Cancer Diagnosis and Therapy

Pavla Martinkova et al.

ADVANCED HEALTHCARE MATERIALS (2018)

Review Chemistry, Multidisciplinary

Emerging Strategies of Cancer Therapy Based on Ferroptosis

Zheyu Shen et al.

ADVANCED MATERIALS (2018)

Article Biochemistry & Molecular Biology

HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models

Xiangju Yin et al.

ANTIOXIDANTS & REDOX SIGNALING (2018)

Article Hematology

Ferritin iron regulators, PCBP1 and NCOA4, respond to cellular iron status in developing red cells

Moon-Suhn Ryu et al.

BLOOD CELLS MOLECULES AND DISEASES (2018)

Article Immunology

Human lactoferrin attenuates the proinflammatory response of neonatal monocyte-derived macrophages

L. Wisgrill et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2018)

Review Oncology

Targeting STEAP1 Protein in Human Cancer: Current Trends and Future Challenges

J. Barroca-Ferreira et al.

CURRENT CANCER DRUG TARGETS (2018)

Article Biochemistry & Molecular Biology

NDRG2 suppresses proliferation, migration, invasion and epithelial-mesenchymal transition of esophageal cancer cells through regulating the AKT/XIAP signaling pathway

Cheng-Liang Yang et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Alterations in Cellular Iron Metabolism Provide More Therapeutic Opportunities for Cancer

Liangfu Zhou et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Medicine, Research & Experimental

Iron Oxide Nanoparticles-Based Vaccine Delivery for Cancer Treatment

Yi Zhao et al.

MOLECULAR PHARMACEUTICS (2018)

Article Multidisciplinary Sciences

Cell iron status influences macrophage polarization

Rafiou Agoro et al.

PLOS ONE (2018)

Article Multidisciplinary Sciences

Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes

Erfei Song et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Multidisciplinary Sciences

Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding

Hou-Fu Guo et al.

NATURE COMMUNICATIONS (2018)

Article

NGAL promotes recruitment of tumor infiltrating leukocytes

Francesco Pacifico et al.

Oncotarget (2018)

Article Multidisciplinary Sciences

STEAP2 Knockdown Reduces the Invasive Potential of Prostate Cancer Cells

Stephanie E. A. Burnell et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese

Natascha A. Wolff et al.

SCIENTIFIC REPORTS (2018)

Review Pharmacology & Pharmacy

The Role of Ferroptosis in Cancer Development and Treatment Response

Bin Lu et al.

FRONTIERS IN PHARMACOLOGY (2018)

Article Chemistry, Multidisciplinary

The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin

Xiaoli Huang et al.

ACS CENTRAL SCIENCE (2018)

Article Nanoscience & Nanotechnology

Blocking Autophagic Flux Enhances Iron Oxide Nanoparticle Photothermal Therapeutic Efficiency in Cancer Treatment

Xiaoqing Ren et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Review Nutrition & Dietetics

Iron and Cancer

Suzy V. Torti et al.

ANNUAL REVIEW OF NUTRITION, VOL 38 (2018)

Review Biochemistry & Molecular Biology

Iron-mediated oxidative cell death is a potential contributor to neuronal dysfunction induced by neonatal hemolytic hyperbilirubinemia

Alena Viktorinova

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2018)

Review Cell Biology

Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases

Mingzhu Tang et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

Review Oncology

A promising new approach to cancer therapy: Targeting iron metabolism in cancer stem cells

Mouradi El Hout et al.

SEMINARS IN CANCER BIOLOGY (2018)

Article Multidisciplinary Sciences

Calcium is an essential cofactor for metal efflux by the ferroportin transporter family

Chandrika N. Deshpande et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker

Mark C. Anderson et al.

CELL CHEMICAL BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Differential regulation of hepcidin in cancer and non-cancer tissues and its clinical implications

Driton Vela et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2018)

Review Chemistry, Medicinal

Anemia and Iron Deficiency in Cancer Patients: Role of Iron Replacement Therapy

Fabiana Busti et al.

PHARMACEUTICALS (2018)

Article Biochemistry & Molecular Biology

Correlation between the concentrations of lactoferrin and neutrophil gelatinase-associated lipocalin in meconium

Barbara Lisowska-Myjak et al.

BIOMETALS (2018)

Article Hematology

Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency

Masahiro Kobayashi et al.

HAEMATOLOGICA (2017)

Article Hematology

Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency

Masahiro Kobayashi et al.

HAEMATOLOGICA (2017)

Review Biochemistry & Molecular Biology

Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosis

Charlie J. Pyle et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Nanoscience & Nanotechnology

IONP-doped nanoparticles for highly effective NIR-controlled drug release and combination tumor therapy

Xudong Fu et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

Review Biochemistry & Molecular Biology

Molecular Regulation of Cellular Iron Balance

Stefania Recalcati et al.

IUBMB LIFE (2017)

Review Biochemistry & Molecular Biology

Interplay of the iron-regulated metastasis suppressor NDRG1 with epidermal growth factor receptor (EGFR) and oncogenic signaling

Sharleen V. Menezes et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Article Medicine, Research & Experimental

Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2

Xiaoyan Yang et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Multidisciplinary Sciences

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

Samantha W. Alvarez et al.

NATURE (2017)

Review Biotechnology & Applied Microbiology

Targeting iron metabolism in drug discovery and delivery

Bart J. Crielaard et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Article Biophysics

Inhibition of prostate cancer proliferation by Deferiprone

Rui V. Simoes et al.

NMR IN BIOMEDICINE (2017)

Article Multidisciplinary Sciences

Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer

Xiang Xue et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Hematology

Iron metabolism: State of the art

R. Daher et al.

TRANSFUSION CLINIQUE ET BIOLOGIQUE (2017)

Article Multidisciplinary Sciences

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

Sant-Rayn Pasricha et al.

NATURE COMMUNICATIONS (2017)

Article Immunology

Iron Induces Anti-tumor Activity in Tumor-Associcated Macrophages

Milene Costa da Silva et al.

FRONTIERS IN IMMUNOLOGY (2017)

Review Oncology

JARID1 Histone Demethylases: Emerging Targets in Cancer

Kayla M. Harmeyer et al.

TRENDS IN CANCER (2017)

Review Biochemistry & Molecular Biology

A Red Carpet for Iron Metabolism

Martina U. Muckenthaler et al.

Article Cell Biology

p53 genes function to restrain mobile elements

Annika Wylie et al.

GENES & DEVELOPMENT (2016)

Article Genetics & Heredity

miR-20a regulates expression of the iron exporter ferroportin in lung cancer

Kamesh R. Babu et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2016)

Article Biochemistry & Molecular Biology

Iron participated in breast cancer chemoresistance by reinforcing IL-6 paracrine loop

Jing Li et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Review Biochemistry & Molecular Biology

Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy

Saverio Candido et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)

Article Pediatrics

Overview of Lactoferrin as a Natural Immune Modulator

Dominique Legrand

JOURNAL OF PEDIATRICS (2016)

Article Biochemistry & Molecular Biology

An important role of the hepcidin-ferroportin signaling in affecting tumor growth and metastasis

Wenli Guo et al.

ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2015)

Article Biochemistry & Molecular Biology

The mechanism of ageing: primary role of transposable elements in genome disintegration

Adam Sturm et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Article Biochemistry & Molecular Biology

Oxidative stress alters global histone modification and DNA methylation

Yingmei Niu et al.

FREE RADICAL BIOLOGY AND MEDICINE (2015)

Review Immunology

Macrophage iron homeostasis and polarization in the context of cancer

Michaela Jung et al.

IMMUNOBIOLOGY (2015)

Article Hematology

Increased expression of HIF2 during iron deficiency-associated megakaryocytic differentiation

K. Jimenez et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2015)

Article Oncology

Decreased expression of ferroportin in prostate cancer

Dong Xue et al.

ONCOLOGY LETTERS (2015)

Review Biotechnology & Applied Microbiology

Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature

Maura Di Nicola et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Review Immunology

Iron homeostasis in host defence and inflammation

Tomas Ganz et al.

NATURE REVIEWS IMMUNOLOGY (2015)

Article Nanoscience & Nanotechnology

Synthesis of Multifunctional Fe3O4-CdSe/ZnS Nanoclusters Coated with Lipid A toward Dendritic Cell-Based Immunotherapy

Jinhoo Jeong et al.

ACS APPLIED MATERIALS & INTERFACES (2014)

Article Biochemistry & Molecular Biology

Iron Oxide Nanoparticles Induce Oxidative Stress, DNA Damage, and Caspase Activation in the Human Breast Cancer Cell Line

Saud Alarifi et al.

BIOLOGICAL TRACE ELEMENT RESEARCH (2014)

Editorial Material Hematology

New signaling pathways for hepcidin regulation

Paolo Arosio

BLOOD (2014)

Article Oncology

A role for STEAP2 in prostate cancer progression

Helen Whiteland et al.

CLINICAL & EXPERIMENTAL METASTASIS (2014)

Article Biochemistry & Molecular Biology

Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism

Svitlana Shpyleva et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism

Bailin Zhao et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Multidisciplinary Sciences

Epigenetic role for the conserved Fe-S cluster biogenesis protein AtDRE2 in Arabidopsis thaliana

Diana Mihaela Buzas et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Genetics & Heredity

Connections between TET proteins and aberrant DNA modification in cancer

Yun Huang et al.

TRENDS IN GENETICS (2014)

Review Pharmacology & Pharmacy

The IRP/IRE system in vivo: insights from mouse models

Nicole Wilkinson et al.

FRONTIERS IN PHARMACOLOGY (2014)

Review Hematology

Efficacy and safety of deferasirox in myelodysplastic syndromes

Massimo Breccia et al.

ANNALS OF HEMATOLOGY (2013)

Review Biochemistry & Molecular Biology

Novel Chelators for Cancer Treatment: Where Are We Now?

Angelica M. Merlot et al.

ANTIOXIDANTS & REDOX SIGNALING (2013)

Review Biochemistry & Molecular Biology

A mechanistic overview of TET-mediated 5-methylcytosine oxidation

V. K. Chaithanya Ponnaluri et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

Article Biochemistry & Molecular Biology

Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis

Erawan Borkham-Kamphorst et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)

Article Biochemistry & Molecular Biology

CD163 Binding to Haptoglobin-Hemoglobin Complexes Involves a Dual-point Electrostatic Receptor-Ligand Pairing

Marianne Jensby Nielsen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Hematology

The regulation of iron metabolism in the mononuclear phagocyte system

Wei-Na Kong et al.

EXPERT REVIEW OF HEMATOLOGY (2013)

Article Genetics & Heredity

Iron-Responsive miR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin

Carolyn Sangokoya et al.

PLOS GENETICS (2013)

Review Oncology

Iron and cancer: more ore to be mined

Suzy V. Torti et al.

NATURE REVIEWS CANCER (2013)

Article Biochemistry & Molecular Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon et al.

Article Biochemistry & Molecular Biology

Micromanaging Iron Homeostasis HYPOXIA-INDUCIBLE MICRO-RNA-210 SUPPRESSES IRON HOMEOSTASIS-RELATED PROTEINS

Yusuke Yoshioka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

The iron regulatory hormone hepcidin inhibits expression of iron release as well as iron uptake proteins in J774 cells

Fang Du et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2012)

Review Oncology

STEAP Proteins: From Structure to Applications in Cancer Therapy

Ines M. Gomes et al.

MOLECULAR CANCER RESEARCH (2012)

Article Oncology

Role of ferritin alterations in human breast cancer cells

Svitlana I. Shpyleva et al.

BREAST CANCER RESEARCH AND TREATMENT (2011)

Article Oncology

An Iron Regulatory Gene Signature Predicts Outcome in Breast Cancer

Lance D. Miller et al.

CANCER RESEARCH (2011)

Article Oncology

The role of iron in tumour cell proliferation

Juan Luis Steegmann-Olmedillas

CLINICAL & TRANSLATIONAL ONCOLOGY (2011)

Article Medicine, Research & Experimental

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

Mirco Castoldi et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Review Biochemistry & Molecular Biology

Two to Tango: Regulation of Mammalian Iron Metabolism

Matthias W. Hentze et al.

Article Hematology

Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells

Immacolata Andolfo et al.

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2010)

Article Biochemistry & Molecular Biology

miR-584 mediates post-transcriptional expression of lactoferrin receptor in Caco-2 cells and in mouse small intestine during the perinatal period

Y. Liao et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)

Article Chemistry, Multidisciplinary

The Immunotherapeutic Effect of Fe3O4 Nanoparticles as Adjuvants on Mice H-22 Live Cancer

Hui Liu et al.

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2010)

Article Nutrition & Dietetics

miR-214 Regulates Lactoferrin Expression and Pro-Apoptotic Function in Mammary Epithelial Cells

Yalin Liao et al.

JOURNAL OF NUTRITION (2010)

Article Cell Biology

Scara5 Is a Ferritin Receptor Mediating Non-Transferrin Iron Delivery

Jau Yi Li et al.

DEVELOPMENTAL CELL (2009)

Article Hematology

miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation

Dale G. Schaar et al.

EXPERIMENTAL HEMATOLOGY (2009)

Review Oncology

Redox signaling and cancer: The role of labile iron

Dimitrios Galaris et al.

CANCER LETTERS (2008)

Article Oncology

Does excess iron play a role in breast carcinogenesis? an unresolved hypothesis

Geoffrey C. Kabat et al.

CANCER CAUSES & CONTROL (2007)

Review Cell Biology

Tuning cell cycle regulation with an iron key

Yu Yu et al.

CELL CYCLE (2007)

Article Gastroenterology & Hepatology

Modulation of iron transport proteins in human colorectal carcinogenesis

M. J. Brookes et al.

Review Biochemistry & Molecular Biology

Structural studies on 2-oxoglutarate oxygenases and related double-stranded β-helix fold proteins

Ian J. Clifton et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2006)

Review Biotechnology & Applied Microbiology

Iron overload and its association with cancer risk in humans: evidence for iron as a carcinogenic metal

Xi Huang

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2003)

Review Biochemistry & Molecular Biology

The role of iron in cell cycle progression and the proliferation of neoplastic cells

NTV Le et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2002)

Review Oncology

The iron metabolism of neoplastic cells: alterations that facilitate proliferation?

JC Kwok et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2002)