Journal
IMMUNITY
Volume 49, Issue 6, Pages 999-1001Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2018.12.004
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In allergic patients, small amounts of allergen activate mast cells and trigger an immune cascade that can result in anaphylactic shock. In a recent issue of Science, Choi et al. (2018) show that dendritic cells sample the lumen of blood vessels and use microvesicles to trigger mast cell degranulation and anaphylaxis.
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