RuII-Catalysed Regioselective C-N Bond Formation of Indolines and Carbazole with Acyl Azides

Ru-II-catalysed pyrimidine directed coupling of the C-7 C-H bond of indolines with acyl azides as a nitrogen surrogate has been developed to produce acyl amides at room temperature. The reaction of aryl, heteroaryl and alpha,beta-unsaturated acyl azides can be accomplished in good yields. The procedure can be extended to the C1-amidation of carbazole with moderate yields. The substrate scope, use of less expensive Ru-catalysis, and oxidant-free conditions are the significant practical features.