Journal
DRUG DISCOVERY TODAY
Volume 24, Issue 2, Pages 629-635Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2018.11.012
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Funding
- National Natural Science Foundation of China (NSFC) [81573347, 81603028]
- Young Scholars Program of Shandong University (YSPSDU) [2016WLJH32]
- Fundamental Research Funds of Shandong University [2017JC006]
- Key Project of NSFC for International Cooperation [81420108027]
- Natural Science Foundation of Shandong Province [ZR2016HB26]
- Key Research and Development Project of Shandong Province [2017CXGC1401]
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Butyrylcholinesterase (BChE) is considered a promising drug target for the treatment of moderate to severe Alzheimer's disease (AD). Here, we review medicinal -chemistry strategies that are currently available for the discovery of selective BChE inhibitors.
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