Journal
COORDINATION CHEMISTRY REVIEWS
Volume 379, Issue -, Pages 147-160Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.ccr.2017.08.003
Keywords
Phthalocyanine; Photodynamic therapy; Photosensitizer; Medicinal; Water soluble; Targeting
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Funding
- National Natural Science Foundation of China [21473033, 21172037]
- Specialized Research Fund for the Doctoral Program of Higher Education [201135141001]
- National Creative Research Initiative programs of the National Research Foundation of Korea (NRF) - Korean government (MSIP) [2012R1A3A2048814]
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Owing to their high extinction coefficients, long absorption wavelengths, and modification tunable photophysical and photochemical properties, phthalocyanines (Pcs) have been widely used as photosensitizers for photodynamic therapy (PDT). Advances made in the past five years on the development of Pcs as medicinal photosensitizers are reviewed and the main design considerations for medicinal applications of these substances are discussed. (C) 2017 Elsevier B.V. All rights reserved.
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