Journal
CLINICAL ORAL IMPLANTS RESEARCH
Volume 29, Issue -, Pages 311-330Publisher
WILEY
DOI: 10.1111/clr.13288
Keywords
aging; Alzheimer's disease; bisphosphonates; cancer; cardiovascular disease; chronic obstructive pulmonary disease; cirrhosis of the liver; dementia; dental implants; depression; diabetes mellitus; geriatric; hypertensive heart disease; hyposalivation; ischemic heart disease; lower respiratory infections; medication-related osteonecrosis of the jaw; meta-analysis; neurocognitive impairment; osteoarthritis; Parkinson's disease; radiotherapy; respiratory diseases; stroke; systematic review
Funding
- International Team for Implantology (ITI Foundation, Basel, Switzerland)
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Objectives: This review evaluated implant survival in geriatric patients (>= 75 years) and/or the impact of systemic medical conditions. Materials and Methods: Systematic literature searches were performed to identify studies reporting on geriatric subjects with dental implants and on implant patients who had any of the seven most common systematic conditions among geriatric patients. Meta-analyses were performed on the postloading implant survival rates. The impact of systemic medical conditions and their respective treatment was qualitatively analyzed. Results: A total of 6,893 studies were identified; of those, 60 studies were included. The fixed-effects model revealed an overall implant survival of 97.3% (95% CI: 94.3, 98.7; studies = 7) and 96.1% (95% CI: 87.3, 98.9; studies = 3), for 1 and 5 years, respectively. In patients with cardiovascular disease, implant survival may be similar or higher compared to healthy patients. High implant survival rates were reported for patients with Parkinson's disease or diabetes mellitus type II. In patients with cancer, implant survival is negatively affected, namely by radiotherapy. Patients with bone metastases receiving high-dose antiresorptive therapy (ART) carry a high risk for complications after implant surgery. Implant survival was reported to be high in patients receiving low-dose ART for treatment of osteoporosis. No evidence was found on implant survival in patients with dementia, respiratory diseases, liver cirrhosis, or osteoarthritis. Conclusions: Implant prostheses in geriatric subjects are a predictable treatment option with a very high rate of implant survival. The functional and psychosocial benefits of such intervention should outweigh the associated risks to common medical conditions.
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