4.6 Article Proceedings Paper

Liquid biopsy: novel technologies and clinical applications

Journal

CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Volume 57, Issue 3, Pages 312-316

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1515/cclm-2018-0610

Keywords

circulating tumor cells; liquid biopsy; minimal residual disease

Funding

  1. EU/IMI consortium CANCER-ID, an Innovative Medicines Initiative Joint Undertaking [115749]
  2. European Union's Seventh Framework Programme (FP7 Health/2007-2013)

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Liquid biopsy was introduced as a new diagnostic concept in 2010 for the analysis of circulating tumor cells (CTCs) and has been now extended to material (in particular DNA) released by tumor cells in the peripheral blood of cancer patients. Over the past decade, various methods have been developed to detect CTCs and ctDNA in the peripheral blood of cancer patients.

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