4.6 Article

Guest Solvent-dependence of the Nanomechanical Response in Substituted Dihydropyrimidinone Crystals

Journal

CHEMISTRY-AN ASIAN JOURNAL
Volume 14, Issue 5, Pages 607-611

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/asia.201801842

Keywords

dihydropyrimidine analogues; nanoindentation; interaction anisotropy; nanomechanical response; solvatomorphs

Funding

  1. SERB, DST (India) [ECR/2016/000827]

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The nanomechanical responses of two crystalline phases of a dihydropyrimidine analogue (1) were similar irrespective of the presence (or absence) of the guest solvent. In contrast, the mechanical responses of two differently solvated forms of the second related (2) crystals were significantly different. These contrasting behaviors are rationalized in terms of intermolecular interactions and energy distributions.

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