4.5 Editorial Material

Key Characteristics Approach to Carcinogenic Hazard Identification

Journal

CHEMICAL RESEARCH IN TOXICOLOGY
Volume 31, Issue 12, Pages 1290-1292

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.chemrestox.8b00321

Keywords

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Funding

  1. U.S. National Institutes of Health [U01 CA33193]
  2. NIEHS Superfund Research Program [NIH P42ES004705]
  3. Office of Environmental Health Hazard Assessment of California EPA [17-E0023]
  4. European Union Programme for Employment and Social Innovation EaSI (2014-2020)
  5. NIEHS Superfund Research Program grant [P42ES027704]

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Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to tackle this challenge.

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