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CELLULAR & MOLECULAR BIOLOGY LETTERS (2006)
TLR4 links innate immunity and fatty acid-induced insulin resistance
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JOURNAL OF CLINICAL INVESTIGATION (2006)
Mitochondrial reactive oxygen species and Ca2+ signaling
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AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells
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AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
Transferrin and iron induce insulin resistance of glucose transport in adipocytes
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METABOLISM-CLINICAL AND EXPERIMENTAL (2006)
The effects of insulin on the central nervous system -: Focus on appetite regulation
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HORMONE AND METABOLIC RESEARCH (2006)
Bax inhibition protects against free fatty acid-induced lysosomal permeabilization
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AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
Hedgehog signaling maintains resident hepatic progenitors throughout life
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AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease
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JOURNAL OF GASTROENTEROLOGY (2006)
Treatment of non-alcoholic fatty liver disease
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POSTGRADUATE MEDICAL JOURNAL (2006)
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo
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HEPATOLOGY (2006)
Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it
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MITOCHONDRION (2006)
Insulin resistance, adiponectin, cytokines in NASH: Which is the best target to treat?
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JOURNAL OF HEPATOLOGY (2006)
Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray
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LABORATORY INVESTIGATION (2006)
Gene expression of leptin, resistin, and adiponectin in the white adipose tissue of obese patients with non-alcoholic fatty liver disease and insulin resistance
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OBESITY SURGERY (2006)
Non-alcoholic steatohepatitis: From cell biology to clinical practice
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JOURNAL OF HEPATOLOGY (2006)
Relationship between in vivo chlorzoxazone hydroxylation, hepatic cytochrorne P450 2E1 content and liver injury in obese non-alcoholic fatty liver disease patients
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HEPATOLOGY RESEARCH (2006)
Review article: hepatic steatosis and insulin resistance
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ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2005)
Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome
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HEPATOLOGY RESEARCH (2005)
Clinicopathological significance of oxidative cellular damage in non-alcoholic fatty liver diseases
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HEPATOLOGY RESEARCH (2005)
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HEPATOLOGY RESEARCH (2005)
Leptin enhances TNF-α production via p38 and JNK MAPK in LPS-stimulated Kupffer cells
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LIFE SCIENCES (2005)
Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor α-induced hepatocyte apoptosis
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GASTROENTEROLOGY (2005)
Plasma adiponectin in nonalcoholic fatty liver is related to hepatic insulin resistance and hepatic fat content, not to liver disease severity
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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Caspase-10 triggers bid cleavage and caspase cascade activation in FasL-induced apoptosis
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Oxidative stress stimulates proliferation and invasiveness of hepatic stellate cells via a MMP2-mediated mechanism
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HEPATOLOGY (2005)
Insulin resistance, the metabolic syndrome, and nonalcoholic fatty liver disease
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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Fat in the liver and insulin resistance
H Yki-Jarvinen
ANNALS OF MEDICINE (2005)
Adiponectin and its receptors in non-alcoholic steatohepatitis
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GUT (2005)
The weight of leptin in immunity
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NATURE REVIEWS IMMUNOLOGY (2004)
Long term prognosis of fatty liver: risk of chronic liver disease and death
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GUT (2004)
The ins and outs of mitochondrial dysfunction in NASH
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DIABETES & METABOLISM (2004)
Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients
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CLINICAL SCIENCE (2004)
Hepatocyte apoptosis, expression of death receptors, and activation of NF-κB in the liver of nonalcoholic and alcoholic steatohepatitis patients
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AMERICAN JOURNAL OF GASTROENTEROLOGY (2004)
Role of resistin in diet-induced hepatic insulin resistance
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JOURNAL OF CLINICAL INVESTIGATION (2004)
Beyond insulin resistance in NASH:: TNF-α or adiponectin?
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HEPATOLOGY (2004)
Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition
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DIABETOLOGIA (2004)
Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice
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JOURNAL OF HEPATOLOGY (2003)
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-α, overexpressed in human fat cells from insulin-resistant subjects
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
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HEPATOLOGY (2003)
Ferritins can regulate the secretion of apolipoprotein B
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hepatocyte apoptosis and Fas expression are prominent features of human nonalcoholic steatohepatitis
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GASTROENTEROLOGY (2003)
Molecular mechanisms of insulin receptor substrate protein-mediated modulation of insulin signalling
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FEBS LETTERS (2003)
Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism.: I.: PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling
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MOLECULAR ENDOCRINOLOGY (2003)
Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis
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HEPATOLOGY (2003)
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
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HEPATOLOGY (2003)
TRAF6-NF-κB pathway is essential for interleukin-1-induced TLR2 expression and its functional response to TLR2 ligand in murine hepatocytes
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IMMUNOLOGY (2003)
BAX and BAK regulation of endoplasmic reticulum Ca2+:: A control point for apoptosis
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SCIENCE (2003)
Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
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HEPATOLOGY (2003)
Hepatic cytochrome p450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis
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HEPATOLOGY (2003)
Obesity is associated with macrophage accumulation in adipose tissue
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JOURNAL OF CLINICAL INVESTIGATION (2003)
Apoptosis-inducing factor (AIF):: key to the conserved caspase-independent pathways of cell death?
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JOURNAL OF CELL SCIENCE (2002)
An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Medical progress - Nonalcoholic fatty liver disease
P Angulo
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Dietary polyunsaturated fatty acids and regulation of gene transcription
DB Jump
CURRENT OPINION IN LIPIDOLOGY (2002)
Apolipoprotein synthesis in nonalcoholic steatohepatitis
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HEPATOLOGY (2002)
Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2
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EMBO JOURNAL (2001)
Liver inflammatory cells, apoptosis, regeneration and stellate cell activation in non-alcoholic steatohepatitis
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DIGESTIVE AND LIVER DISEASE (2001)
High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis
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HEPATOLOGY (2001)
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Hepatic glucose uptake, gluconeogenesis and the regulation of glycogen synthesis
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DIABETES-METABOLISM RESEARCH AND REVIEWS (2001)
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
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GASTROENTEROLOGY (2001)
Mechanisms of disease: Cytokines in alcoholic and nonalcoholic steatohepatitis.
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NEW ENGLAND JOURNAL OF MEDICINE (2000)
Cellular mechanisms of insulin resistance
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JOURNAL OF CLINICAL INVESTIGATION (2000)
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2000)
SOCS-3 is an insulin-induced negative regulator of insulin signaling
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
SL Friedman
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Grading and staging the histopathological lesions of chronic hepatitis. The Knodell histology activity index and beyond
EM Brunt
HEPATOLOGY (2000)
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